Evidence map›Paper›PMID 34285749›Full record

ArticleThe Pan African medical journal2021

Neurological manifestations in patients with symptomatic COVID-19 admitted to the Bafoussam Regional Hospital, Cameroon.

Yannick Fogoum Fogang, Michel Noubom, Pierre-Yves Bassong, Paul Chimi Mbonda, Iliassou Njoudap Mfopou, Daniel Massi Gams, Callixte Tegueu Kuate, Joseph Kamtchum-Tatuene

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Article in The Pan African medical journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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3citing papers in PubMed
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Yannick Fogoum FogangFaculty of Medicine and Pharmaceutical Sciences, University of Dschang, Dschang, Cameroon.
Michel NoubomFaculty of Medicine and Pharmaceutical Sciences, University of Dschang, Dschang, Cameroon.
Pierre-Yves BassongFaculty of Medicine and Pharmaceutical Sciences, University of Bamenda, Bamenda, Cameroon.
Paul Chimi MbondaFaculty of Medicine and Biomedical Sciences, University of Yaounde I, Yaounde, Cameroon.
Iliassou Njoudap MfopouBafoussam Regional Hospital, Bafoussam, Cameroon.
Daniel Massi GamsFaculty of Health Sciences, University of Buea, Buea, Cameroon.
Callixte Tegueu KuateFaculty of Medicine and Biomedical Sciences, University of Yaounde I, Yaounde, Cameroon.
Joseph Kamtchum-TatueneNeuroscience and Mental Health Institute, Faculty of Medicine and Dentistry, University of Alberta, Alberta, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionalthough the main manifestations of COVID-19 are respiratory, several neurological symptoms and complications have also been reported. The pandemic seems to have some epidemiological specificities in sub-Saharan Africa, and this may be reflected in the type and frequency of neurological symptoms. This study aimed to report neurological manifestations associated with symptomatic COVID-19 in a sub-Saharan African setting.

methodswe conducted a retrospective review of symptomatic PCR-confirmed COVID-19 cases admitted to the Bafoussam Regional Hospital between March and September 2020. Patients' files were reviewed at discharge by a consultant neurologist. Socio-demographic characteristics, co-morbidities, symptoms on admission, neurological symptoms during hospitalization, management, and in-hospital outcome were recorded. Comparisons between patients with and without neurological symptoms were performed using Fisher's exact and Mann-Whitney U test.

resultswe enrolled 177 symptomatic patients (68% men). Mean age was 54.6 ± 17.8 years (range 2-99 years). Co-morbidities were present in 57.6% of patients, including hypertension (27.1%) and diabetes mellitus (25.4%). Neurological symptoms were found in 113 (63.8%) patients. The most frequent were headache (39.0%), myalgia (35.6%), anosmia (11.9%), impaired consciousness (10.7%) and delirium (5.6%). Regarding the presenting symptoms, fever was more frequent in patients with neurological symptoms than in those without (81.4% versus 50.0%, p< 0.001), while digestive symptoms were less frequent in patients with neurological symptoms (0.9% versus 9.4%, p= 0.004).

conclusionneurological manifestations are frequent and heterogeneous in patients with symptomatic COVID-19. Further studies are needed to clarify the pathophysiology of neurological symptoms in COVID-19 and their impact on patients' long-term outcome.

Indexed as

HospitalizationAdolescentAdultAgedAged, 80 and overCameroonChildChild, PreschoolComorbidityCOVID-19FemaleFeverHumansMaleMiddle AgedNervous System DiseasesAfricaanosmiaCoronavirusCOVID-19headache

Identifiers

PMID34285749
PMCPMC8265250

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.