Evidence map›Paper›PMID 34285718›Full record

ArticleTherapeutic advances in neurological disorders2021

Persistent decline of hospitalizations for acute stroke and acute coronary syndrome during the second wave of the COVID-19 pandemic in Greece: collateral damage unaffected.

Christos Katsouras, Georgios Tsivgoulis, Michail Papafaklis, Theodore Karapanayiotides, Dimitrios Alexopoulos, Evangelos Ntais, Georgia Papagiannopoulou, Ioanna Koutroulou, Antonios Ziakas, Georgios Sianos and 9 more

Open access · goldAbstract read
In one paragraph

Article in Therapeutic advances in neurological disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 13 citations in OpenAlex.

  1. Observational
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  4. Stroke admissions during the COVID-19 pandemic: a single-center retrospective analysis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022
    Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 3 institutions in 1 country.

Christos KatsourasSecond Department of Cardiology, University Hospital of Ioannina, University of Ioannina, Ioannina, Greece.
Georgios TsivgoulisSecond Department of Neurology, ATTIKON University Hospital, National and Kapodistrian University of Athens, Athens, Greece.ORCID https://orcid.org/0000-0002-0640-3797
Michail PapafaklisSecond Department of Cardiology, University Hospital of Ioannina, University of Ioannina, Ioannina, Greece.
Theodore KarapanayiotidesSecond Department of Neurology, Faculty of Health Sciences, School of Medicine, AHEPA University Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Dimitrios AlexopoulosDepartment of Cardiology, ATTIKON University Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Evangelos NtaisDepartment of Neurology, University Hospital of Ioannina, University of Ioannina, Ioannina, Greece.
Georgia PapagiannopoulouSecond Department of Neurology, ATTIKON University Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Ioanna KoutroulouSecond Department of Neurology, Faculty of Health Sciences, School of Medicine, AHEPA University Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece.ORCID https://orcid.org/0000-0001-5043-6521
Antonios ZiakasDepartment of Cardiology, Faculty of Medicine, School of Health Sciences, AHEPA University Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Georgios SianosDepartment of Cardiology, Faculty of Medicine, School of Health Sciences, AHEPA University Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Antonios KouparanisDepartment of Cardiology, Faculty of Medicine, School of Health Sciences, AHEPA University Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Paraskevi TrivilouDepartment of Cardiology, ATTIKON University Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Christos BallasSecond Department of Cardiology, University Hospital of Ioannina, University of Ioannina, Ioannina, Greece.
Ioanna SamaraSecond Department of Cardiology, University Hospital of Ioannina, University of Ioannina, Ioannina, Greece.
Maria KosmidouDepartment of Neurology, University Hospital of Ioannina, University of Ioannina, Ioannina, Greece.
Lina PalaiodimouSecond Department of Neurology, ATTIKON University Hospital, National and Kapodistrian University of Athens, Athens, Greece.ORCID https://orcid.org/0000-0001-7757-609X
Nikolaos GrigoriadisSecond Department of Neurology, Faculty of Health Sciences, School of Medicine, AHEPA University Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Lampros K MichalisSecond Department of Cardiology, University Hospital of Ioannina, University of Ioannina, Ioannina, Greece.
Sotirios GiannopoulosSecond Department of Neurology, ATTIKON University Hospital, National and Kapodistrian University of Athens, Athens, Greece.ORCID https://orcid.org/0000-0001-7443-5179
University of Ioannina · GRAristotle University of Thessaloniki · GRNational and Kapodistrian University of Athens · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAn alarming cerebro/cardiovascular collateral damage, reflected by a decline in admissions for acute stroke (AS) and acute coronary syndrome (ACS), was observed during the initial phase of the COVID-19 pandemic, thereby leading to a re-design of public campaigns. However, there are limited data regarding the AS and ACS hospitalization rates during the second wave of the pandemic, which was followed by re-imposition of lockdowns.

methodsWe calculated the rate of AS and ACS hospitalizations from three representative tertiary care hospitals in Greece during a 2-month period (November-December 2020) of the second wave of the COVID-19 pandemic compared with the corresponding control period in 2019 from three representative tertiary care hospitals in Greece. This was a follow-up study with identical design to our previous report evaluating AS and ACS hospitalizations during the first wave of the pandemic (March-April 2020).

resultsCompared with 2019, there was a 34% relative reduction of AS hospitalizations [incidence rate ratio (IRR): 0.66, 95% confidence interval (CI): 0.48-0.92,

conclusionAS and ACS hospitalizations were persistently reduced during the second wave of the COVID-19 pandemic compared with 2019 in Greece. This decline was similar to the observations during the first wave despite the large differences in the epidemiological COVID-19 burden. Lockdowns, a common characteristic in both waves, appear to have a detrimental indirect impact on cerebro/cardiovascular diseases in the general population.

Indexed as

acute coronary syndromesadmissionsCOVID-19Greeceintracerebral haemorrhageischaemic strokestroke

Identifiers

PMID34285718
PMCPMC8267023
OpenAlexW3178750217

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.