Evidence map›Paper›PMID 34285338›Full record

ArticleScientific reports2021

Indexing cerebrovascular health using near-infrared spectroscopy.

Rashid Afkhami, Frederick R Walker, Saadallah Ramadan, Rachel Wong, Sarah J Johnson

Abstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Rashid AfkhamiSchool of Engineering, University of Newcastle, Callaghan, Australia. rashid.afkhami@newcastle.edu.au.
Frederick R WalkerSchool of Biomedical Sciences and Pharmacy, University of Newcastle, Callaghan, Australia.
Saadallah RamadanSchool of Health Sciences, University of Newcastle, Callaghan, Australia.
Rachel WongSchool of Biomedical Sciences and Pharmacy, University of Newcastle, Callaghan, Australia.
Sarah J JohnsonSchool of Engineering, University of Newcastle, Callaghan, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Near-infrared spectroscopy (NiRS) is a relatively new technology of brain imaging with its potential in the assessment of cerebrovascular health only recently discovered. Encouraging early results suggest that NiRS can be used as an inexpensive and portable cerebrovascular health tracking device using a recently proposed pulse relaxation function (PReFx). In this paper, we propose a new NiRS timing index, [Formula: see text], of cerebrovascular health. [Formula: see text] is a novel use of the NiRS technology. [Formula: see text] is motivated by the previously proved relationship of the timing of the reflected wave with vascular resistance and compliance in the context of pressure waveforms. We correlated both [Formula: see text] and PReFx against age, a non-exercise cardiorespiratory fitness (CRF) index, and two existing indices of cerebrovascular health, namely transcranial Doppler (TCD) augmentation index, [Formula: see text], and magnetic resonance imaging (MRI) blood flow pulsatility index, [Formula: see text]. The [Formula: see text] correlations with Age, CRF, [Formula: see text] and [Formula: see text] all are significant, i.e., [Formula: see text] ([Formula: see text]), [Formula: see text] ([Formula: see text]), [Formula: see text] ([Formula: see text]) and [Formula: see text] ([Formula: see text]), respectively. PReFx, however, did not have significant correlations with any of the vascular health factors. The proposed timing index is a reliable indicator of cerebrovascular aging factors in the NiRS waveform.

Indexed as

Vascular StiffnessAdultAgedCardiorespiratory FitnessFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedSpectroscopy, Near-InfraredUltrasonography, Doppler, Transcranial

Identifiers

PMID34285338
PMCPMC8292377

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.