Evidence map›Paper›PMID 34285282›Full record

Trial reportScientific reports2021

Concomitant oral intake of purified clinoptilolite tuff (G-PUR) reduces enteral lead uptake in healthy humans.

Karolina Samekova, Christa Firbas, Johanna Irrgeher, Christine Opper, Thomas Prohaska, Anika Retzmann, Cornelius Tschegg, Claudia Meisslitzer, Anastassiya Tchaikovsky, Ghazaleh Gouya and 2 more

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

  1. Trial
  2. Topically administered purified clinoptilolite-tuff for the treatment of cutaneous wounds: A prospective, randomised phase I clinical trial.Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society · 2022
    Trial
  3. Article
  4. Article
  5. PMA-Zeolite: Chemistry and Diverse Medical Applications.Journal of functional biomaterials · 2024
    Review
  6. Article
  7. Article
  8. Enriched stableAnalytical and bioanalytical chemistry · 2023
    Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Karolina SamekovaDepartment of Clinical Pharmacology, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria.
Christa FirbasDepartment of Clinical Pharmacology, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria.
Johanna IrrgeherDepartment of General, Analytical and Physical Chemistry, Montanuniversität Leoben, Franz-Josef-Straße 18, 8700, Leoben, Austria.
Christine OpperDepartment of General, Analytical and Physical Chemistry, Montanuniversität Leoben, Franz-Josef-Straße 18, 8700, Leoben, Austria.
Thomas ProhaskaDepartment of General, Analytical and Physical Chemistry, Montanuniversität Leoben, Franz-Josef-Straße 18, 8700, Leoben, Austria.
Anika RetzmannDepartment of General, Analytical and Physical Chemistry, Montanuniversität Leoben, Franz-Josef-Straße 18, 8700, Leoben, Austria.
Cornelius TscheggGlock Health, Science and Research GmbH, Hausfeldstraße 17, 2232, Deutsch-Wagram, Austria.
Claudia MeisslitzerGlock Health, Science and Research GmbH, Hausfeldstraße 17, 2232, Deutsch-Wagram, Austria.
Anastassiya TchaikovskyGlock Health, Science and Research GmbH, Hausfeldstraße 17, 2232, Deutsch-Wagram, Austria.
Ghazaleh GouyaGouya Insights, Elisabethstrasse 22/12, 1010, Vienna, Austria.
Michael FreissmuthInstitute of Pharmacology and the Gaston H. Glock Research Laboratories for Exploratory Drug Development, Center of Physiology and Pharmacology, Medical University of Vienna, Währingerstrasse 13a, Vienna, Austria.
Michael WolztDepartment of Clinical Pharmacology, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria. michael.wolzt@meduniwien.ac.at.
Medical University of Vienna · ATMontanuniversität Leoben · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lead exposure can cause substantial organ damage. Enteral lead absorption may be reduced by concomitant intake of clinoptilolite tuff, a zeolite from natural sources. This study aimed to assess the effect of purified clinoptilolite tuff (G-PUR) on enteral lead uptake in adults using stable lead isotope

Indexed as

AdultDouble-Blind MethodFemaleHumansLeadLead PoisoningMaleZeolitesclinoptiloliteLeadZeolites

Identifiers

PMID34285282
PMCPMC8292361
OpenAlexW3185071890

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.