ArticleNature communications2021
Self-healing polyurethane-elastomer with mechanical tunability for multiple biomedical applications in vivo.
Article in Nature communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 44 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
44 citing papers in PubMed, 212 citations in OpenAlex.
- Artificial intelligence and peripheral neuropathies: Strategies for the development, application, and repair of regenerative biomaterials.Neural regeneration research · 2026Article
- An Extravascular Synergistic Cocktail Therapeutic Strategy Based on Lanifibranor Loaded Self-Healing Bioelastomer for Abdominal Aortic Aneurysms.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- Aerogel-involved triple-state viscoelastic fluidic materials enable high-efficiency dual-purpose energy management.Nature communications · 2026Article
- A conformable shape-stable self-healing polymer platform for continuous wireless arterial pulse monitoring.Nature communications · 2026Article
- Design guidelines for self-healing materials in soft electronics.Nano convergence · 2026Review
- Multi-Functional Adaptive Interfaces for Next-Generation Wearable and Implantable Bioelectronics.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- Sublytic pyroptosis blocks Schwann cell remyelination through caspase-1-mediated Tyro3 cleavage.Journal of neuroinflammation · 2026Article
- Recent progress of 3D printed responsive scaffolds for bone repair: A review.Materials today. Bio · 2025Review
- Autonomous Implants.Advanced materials (Deerfield Beach, Fla.) · 2025Review
- Multidimensional advances in neural interface technology for peripheral nerve repair: From material innovation to clinical translation.Materials today. Bio · 2025Review
- Bridging small molecule calculations and predictable polymer mechanical properties.Nature communications · 2025Article
- A Body Conformal Ultrasound Receiver for Efficient and Stable Wireless Power Transfer in Deep Percutaneous Charging.Advanced materials (Deerfield Beach, Fla.) · 2025Article
- Colloidal-fibrillar composite gels demonstrate structural reinforcement, secondary fibrillar alignment, and improved vascular healing outcomes.Communications engineering · 2025Article
- Highly Elastic, Biodegradable Polyester-Based Citrate Rubber for 3D Printing in Regenerative Engineering.ACS biomaterials science & engineering · 2025Article
- Rapidly self-healing electronic skin for machine learning-assisted physiological and movement evaluation.Science advances · 2025Article
- Advanced Immunomodulatory Biomaterials for Therapeutic Applications.Advanced healthcare materials · 2025Review
- Self-healing and hyperelastic magneto-iono-elastomers through molecular confinement of magnetic anions.Science advances · 2025Article
- Recent Progress of Soft and Bioactive Materials in Flexible Bioelectronics.Cyborg and bionic systems (Washington, D.C.) · 2025Review
- Synthesis and Characterization of Photocurable Difunctional Monomers for Medical Applications.Polymers · 2024Article
- Article
Corrections and comments
- Erratum issued
Authors and funding
14 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The unique properties of self-healing materials hold great potential in the field of biomedical engineering. Although previous studies have focused on the design and synthesis of self-healing materials, their application in in vivo settings remains limited. Here, we design a series of biodegradable and biocompatible self-healing elastomers (SHEs) with tunable mechanical properties, and apply them to various disease models in vivo, in order to test their reparative potential in multiple tissues and at physiological conditions. We validate the effectiveness of SHEs as promising therapies for aortic aneurysm, nerve coaptation and bone immobilization in three animal models. The data presented here support the translation potential of SHEs in diverse settings, and pave the way for the development of self-healing materials in clinical contexts.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.