Evidence map›Paper›PMID 34285125›Full record

ArticleInternational journal of spine surgery2021

Prevalence of Cannabidiol Use in Patients With Spine Complaints: Results of an Anonymous Survey.

Francis Lovecchio, Mark T Langhans, Tianna Bennett, Michael Steinhaus, Ajay Premkumar, Matthew Cunningham, James Farmer, Todd Albert, Russel Huang, Yoshihiro Katsuura and 6 more

Open access · diamondAbstract read
In one paragraph

Article in International journal of spine surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 1 institution in 1 country.

Francis LovecchioHospital for Special Surgery, Spine Service, New York, New York.
Mark T LanghansHospital for Special Surgery, Spine Service, New York, New York.
Tianna BennettHospital for Special Surgery, Spine Service, New York, New York.
Michael SteinhausHospital for Special Surgery, Spine Service, New York, New York.
Ajay PremkumarHospital for Special Surgery, Spine Service, New York, New York.
Matthew CunninghamHospital for Special Surgery, Spine Service, New York, New York.
James FarmerHospital for Special Surgery, Spine Service, New York, New York.
Todd AlbertHospital for Special Surgery, Spine Service, New York, New York.
Russel HuangHospital for Special Surgery, Spine Service, New York, New York.
Yoshihiro KatsuuraHospital for Special Surgery, Spine Service, New York, New York.
Sheeraz QureshiHospital for Special Surgery, Spine Service, New York, New York.
Frank SchwabHospital for Special Surgery, Spine Service, New York, New York.
Harvinder SandhuHospital for Special Surgery, Spine Service, New York, New York.
Han Jo KimHospital for Special Surgery, Spine Service, New York, New York.
Virginie LafageHospital for Special Surgery, Spine Service, New York, New York.
Sravisht IyerHospital for Special Surgery, Spine Service, New York, New York.
Hospital for Special Surgery · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCannabidiol (CBD) is a cannabis derivative that has been popularized as a medicinal product with analgesic and anti-inflammatory effects. Given the anecdotal observations that several patients have reported use of CBD for spine-related pain, this study was designed to characterize CBD consumption patterns and perceived effects in patients with spine-related complaints.

methodsThe study design was a cross-sectional survey. Over a 4-week period, an anonymous paper survey was administered to all patients presenting for evaluation by 1 of 9 spine surgeons at a single institution. Surveys were given upon registration for the office visit and collected by the office manager or nurse before evaluation by the surgeon. Patients were included regardless of surgical status (ie, preoperative, postoperative, or nonoperative) or region of pathology (lumbar, thoracic, or cervical). The survey consisted of multiple-choice questions on patient patterns of CBD use.

resultsOut of 300 surveys, 214 (71%) were completed. CBD use for spine-related pain was reported by 54 (25.2%) patients. CBD was initially used for potential relief of back pain (66.7%), neck pain (37.0%), leg pain (35.2%), and/or arm pain (9.3%). Users also sought improvements in insomnia (25.9%) and mood (18.5%). Oil was the most popular formulation (64.8%). CBD was most often consumed 2-5 times (40.7%) or 6-10 times (31.5%) per week. The most common source of initial recommendation for CBD was friends or family (75.9%). Reported benefits were pain relief (46.3%), improved sleep (33.3%), and reduced anxiety (20.4%); however, 24.1% of patients reported no benefit from CBD use. The most reported side effect was fatigue (7.4%). Most users (63.0%) would recommend CBD to a friend for pain relief.

conclusionCBD is already used by many patients, and further high-quality research on this supplement is essential. LEVEL OF EVIDENCE: 4. CLINICAL RELEVANCE: CBD is a commonly used by spine patients as an off label treatment.

Indexed as

analgesiaback paincannabidiolneck pain

Identifiers

PMID34285125
PMCPMC8375682
OpenAlexW3183192371

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.