ArticleCMAJ open
Association between preoperative frailty and outcomes among adults undergoing cardiac surgery: a prospective cohort study.
Article in CMAJ open. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 3 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 3 syntheses or guidelines pooled it, 39 citations in OpenAlex.
- Prevalence and risk factors of frailty among cardiac surgery patients: a systematic review and meta-analysis.Annals of medicine · 2025Pooled it
- Meta-analysis of scar formation and depression and anxiety symptoms in patients after cardiac surgery.Frontiers in psychiatry · 2025Pooled it
- Prevalence and unfavorable outcome of frailty in older adults with gastric cancer: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Pooled it
- The Impact of Additional Exercise Interventions on Physical Performance and Muscle Strength of Frail Patients After Open-Heart Surgery: A Randomized Trial.Medicina (Kaunas, Lithuania) · 2025Trial
- Risk Analysis Index Versus mFI-5 for Predicting Outcomes After Uvulopalatopharyngoplasty.The Laryngoscope · 2026Article
- Decision making in chronic subdural haematoma patient referrals in an octogenarian and nonagenarian population - a multi-centre perspective.Irish journal of medical science · 2026Article
- The impact of preoperative weight loss on recovery after cardiac surgery.Heart and vessels · 2026Article
- Core sociodemographic data variables reported in Canadian intensive care unit studies: a scoping review.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2025Review
- Cardiac Rehabilitation After Mitral Valve Intervention: Tailored Assessment, Management, and Exercise Training.Journal of cardiovascular development and disease · 2025Review
- Frailty and long-term survival of non-cancer patients admitted to intensive care after surgery: a retrospective multicentre cohort study.British journal of anaesthesia · 2025Article
- Factors Associated With Postoperative Complications Among Critical Patients Undergoing Open-Heart Surgery: A Cross-Sectional Study.Nursing open · 2025Article
- Frailty in Cardiac Surgery-Assessment Tools, Impact on Outcomes, and Optimisation Strategies: A Narrative Review.Journal of cardiovascular development and disease · 2025Review
- Preoperative Cognitive Optimization and Postoperative Cognitive Outcomes: A Narrative Review.Clinical interventions in aging · 2025Review
- The perioperative frailty index derived from the Chinese hospital information system: a validation study.BMC geriatrics · 2024Article
- Impact of frailty and prefrailty on the mid-term outcomes and rehabilitation course after cardiac surgery.Surgery today · 2024Article
- Post-intensive care syndrome follow-up system after hospital discharge: a narrative review.Journal of intensive care · 2024Review
- Feasibility of frailty screening among patients with advanced heart failure.BMJ open quality · 2023Article
- One-Year Survival after Cardiac Surgery in Frail Older People-Social Support Matters: A Prospective Cohort Study.Journal of clinical medicine · 2023Article
- Does Preoperative Cognitive Optimization Improve Postoperative Outcomes in the Elderly?Journal of clinical medicine · 2022Review
- Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe identification of frailty before complex and invasive procedures may have relevance for prognostic and recovery purposes, to optimally inform patients, caregivers and clinicians about perioperative risk and postoperative care needs. The aim of this study was to estimate the prevalence of frailty and describe the associated clinical course and outcomes of patients referred for nonemergent cardiac surgery.
methodsA prospective cohort of patients aged 50 years and older referred for nonemergent cardiac surgery in Alberta, Canada, from November 2011 to March 2014 were screened preoperatively for frailty, defined as a Clinical Frailty Scale (CFS) score of 5 or greater. Postoperatively, patients were followed by telephone to assess CFS score, health services use and vital status. The primary outcome was all-cause hospital mortality. Secondary outcomes included health services use, hospital discharge disposition, 1-year health-related quality of life and all-cause 5-year mortality.
resultsThe cohort (
interpretationPreoperative frailty was present in 10% of patients and was associated with a higher risk of morbidity and greater health services use. Preoperative frailty has important implications for the postoperative clinical course and resource utilization of patients undergoing cardiac surgery.
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Registered trials
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