Evidence map›Paper›PMID 34284784›Full record

ArticleCardiovascular diabetology2021

Epicardial adipose tissue and severe Coronavirus Disease 19.

Hélène Bihan, Richard Heidar, Aude Beloeuvre, Lucie Allard, Elise Ouedraogo, Sopio Tatulashvili, Yacine Tandjaoui, Stephane Gaudry, Pierre-Yves Brillet, Emmanuel Cosson

Abstract read
In one paragraph

Article in Cardiovascular diabetology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Association of epicardial adipose tissue with the severity and adverse clinical outcomes of COVID-19: A meta-analysis.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Hélène BihanDepartment of Endocrinology-Diabetology-Nutrition, CRNH-IdF, CINFO, AP-HP, Avicenne Hospital, Paris 13 University, Sorbonne Paris Cité, Hôpital Avicenne, 125 route de Stalingrad, 93009, Bobigny, France. helene.bihan@aphp.fr.ORCID 0000-0002-0274-6039
Richard HeidarUnit of Radiology, Avicenne Hospital, Bobigny, France.
Aude BeloeuvreUnit of Intensive Care Medicine, Avicenne Hospital, Bobigny, France.
Lucie AllardDepartment of Endocrinology-Diabetology-Nutrition, CRNH-IdF, CINFO, AP-HP, Avicenne Hospital, Paris 13 University, Sorbonne Paris Cité, Hôpital Avicenne, 125 route de Stalingrad, 93009, Bobigny, France.
Elise OuedraogoDepartment of Infectious Disease, AP-HP Avicenne Hospital, Bobigny, France.
Sopio TatulashviliDepartment of Endocrinology-Diabetology-Nutrition, CRNH-IdF, CINFO, AP-HP, Avicenne Hospital, Paris 13 University, Sorbonne Paris Cité, Hôpital Avicenne, 125 route de Stalingrad, 93009, Bobigny, France.
Yacine TandjaouiUnit of Intensive Care Medicine, Avicenne Hospital, Bobigny, France.
Stephane GaudryUnit of Intensive Care Medicine, Avicenne Hospital, Bobigny, France.
Pierre-Yves BrilletUnit of Radiology, Avicenne Hospital, Bobigny, France.
Emmanuel CossonDepartment of Endocrinology-Diabetology-Nutrition, CRNH-IdF, CINFO, AP-HP, Avicenne Hospital, Paris 13 University, Sorbonne Paris Cité, Hôpital Avicenne, 125 route de Stalingrad, 93009, Bobigny, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBoth visceral adipose tissue and epicardial adipose tissue (EAT) have pro-inflammatory properties. The former is associated with Coronavirus Disease 19 (COVID-19) severity. We aimed to investigate whether an association also exists for EAT. MATERIAL AND

methodsWe retrospectively measured EAT volume using computed tomography (CT) scans (semi-automatic software) of inpatients with COVID-19 and analyzed the correlation between EAT volume and anthropometric characteristics and comorbidities. We then analyzed the clinicobiological and radiological parameters associated with severe COVID-19 (O2 [Formula: see text] 6 l/min), intensive care unit (ICU) admission or death, and 25% or more CT lung involvement, which are three key indicators of COVID-19 severity.

resultsWe included 100 consecutive patients; 63% were men, mean age was 61.8 ± 16.2 years, 47% were obese, 54% had hypertension, 42% diabetes, and 17.2% a cardiovascular event history. Severe COVID-19 (n = 35, 35%) was associated with EAT volume (132 ± 62 vs 104 ± 40 cm

conclusionsOur results suggest that measuring EAT volume on chest CT scans at hospital admission in patients diagnosed with COVID-19 might help to assess the risk of disease aggravation.

Indexed as

Tomography, X-Ray ComputedAdipose TissueAdultAgedAged, 80 and overCOVID-19FemaleHumansIntensive Care UnitsLungMaleMiddle AgedPatient AdmissionPericardiumPredictive Value of TestsPrognosisCOVID-19Epicardial adipose tissue (EAT)Epicardial fat volumeInflammation

Identifiers

PMID34284784
PMCPMC8290380

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.