Evidence map›Paper›PMID 34284246›Full record

ArticleClinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology2021

Auditory neurophysiological development in early childhood: A growth curve modeling approach.

Elaine C Thompson, Ryne Estabrook, Jennifer Krizman, Spencer Smith, Stephanie Huang, Travis White-Schwoch, Trent Nicol, Nina Kraus

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Elaine C ThompsonAuditory Neuroscience Laboratory, Northwestern University, Evanston, IL, USA; Department of Communication Sciences, Northwestern University, Evanston, IL, USA.
Ryne EstabrookDepartment of Psychology, University of Illinois at Chicago, Chicago, IL, USA.
Jennifer KrizmanAuditory Neuroscience Laboratory, Northwestern University, Evanston, IL, USA; Department of Communication Sciences, Northwestern University, Evanston, IL, USA.
Spencer SmithAuditory Neuroscience Laboratory, Northwestern University, Evanston, IL, USA; Department of Communication Sciences, Northwestern University, Evanston, IL, USA.
Stephanie HuangAuditory Neuroscience Laboratory, Northwestern University, Evanston, IL, USA.
Travis White-SchwochAuditory Neuroscience Laboratory, Northwestern University, Evanston, IL, USA; Department of Communication Sciences, Northwestern University, Evanston, IL, USA.
Trent NicolAuditory Neuroscience Laboratory, Northwestern University, Evanston, IL, USA; Department of Communication Sciences, Northwestern University, Evanston, IL, USA.
Nina KrausAuditory Neuroscience Laboratory, Northwestern University, Evanston, IL, USA; Department of Communication Sciences, Northwestern University, Evanston, IL, USA; Institute for Neuroscience, Northwestern University, Evanston, IL, USA; Department of Neurobiology, Northwestern University, Evanston, IL, USA; Department of Otolaryngology, Northwestern University, Chicago, IL, USA. Electronic address: nkraus@northwestern.edu.
Northwestern University · USUniversity of Illinois Chicago · US

Funding

A preschool biomarker for literacyR01HD069414 · NICHD · NORTHWESTERN UNIVERSITY · PI KRAUS, NINA · 2012 to 2016
$1.8M
Hearing in noise in early childhood: neurophysiological, cognitive, and linguistic mechanismsF31DC016205 · NIDCD · NORTHWESTERN UNIVERSITY · PI THOMPSON, ELAINE CHESHIRE · 2017 to 2018
$57k
NICHD NIH HHS R01 HD069414NIDCD NIH HHS F31 DC016205
6 · The paper itself

Abstract

objectiveDuring early childhood, the development of communication skills, such as language and speech perception, relies in part on auditory system maturation. Because auditory behavioral tests engage cognition, mapping auditory maturation in the absence of cognitive influence remains a challenge. Furthermore, longitudinal investigations that capture auditory maturation within and between individuals in this age group are scarce. The goal of this study is to longitudinally measure auditory system maturation in early childhood using an objective approach.

methodsWe collected frequency-following responses (FFR) to speech in 175 children, ages 3-8 years, annually for up to five years. The FFR is an objective measure of sound encoding that predominantly reflects auditory midbrain activity. Eliciting FFRs to speech provides rich details of various aspects of sound processing, namely, neural timing, spectral coding, and response stability. We used growth curve modeling to answer three questions: 1) does sound encoding change across childhood? 2) are there individual differences in sound encoding? and 3) are there individual differences in the development of sound encoding?

resultsSubcortical auditory maturation develops linearly from 3-8 years. With age, FFRs became faster, more robust, and more consistent. Individual differences were evident in each aspect of sound processing, while individual differences in rates of change were observed for spectral coding alone.

conclusionsBy using an objective measure and a longitudinal approach, these results suggest subcortical auditory development continues throughout childhood, and that different facets of auditory processing follow distinct developmental trajectories. SIGNIFICANCE: The present findings improve our understanding of auditory system development in typically-developing children, opening the door for future investigations of disordered sound processing in clinical populations.

Indexed as

Growth ChartsAcoustic StimulationAuditory PerceptionChildChild DevelopmentChild, PreschoolCohort StudiesCross-Sectional StudiesEvoked Potentials, AuditoryFemaleHumansMaleSpeech PerceptionAuditory processingChildhoodDevelopmentGrowth curve modelingLongitudinalNeurophysiology

Identifiers

PMID34284246
PMCPMC8384681
OpenAlexW3175578200

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.