Evidence map›Paper›PMID 34284047›Full record

ArticleJournal of controlled release : official journal of the Controlled Release Society2021

Gadolinium-labeled affibody-XTEN recombinant vector for detection of HER2+ lesions of ovarian cancer lung metastasis using quantitative MRI.

Alireza Nomani, Geng Li, Siavash Yousefi, Shawn Wu, Obeid M Malekshah, Shahryar K Nikkhoi, Mehrdad Pourfathi, Rahim Rizi, Arash Hatefi

Open access · greenAbstract read
In one paragraph

Article in Journal of controlled release : official journal of the Controlled Release Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Alireza NomaniDepartment of Pharmaceutics, Rutgers University, Piscataway, NJ, USA.
Geng LiDepartment of Pharmaceutics, Rutgers University, Piscataway, NJ, USA.
Siavash YousefiDepartment of Radiation Oncology, Stanford University School of Medicine, Stanford, CA, USA.
Shawn WuMolecular Imaging Center, Rutgers University, Piscataway, NJ, USA.
Obeid M MalekshahDepartment of Pharmaceutics, Rutgers University, Piscataway, NJ, USA.
Shahryar K NikkhoiDepartment of Pharmaceutics, Rutgers University, Piscataway, NJ, USA.
Mehrdad PourfathiDepartment of Radiology, University of Pennsylvania, Philadelphia, PA, USA.
Rahim RiziDepartment of Radiology, University of Pennsylvania, Philadelphia, PA, USA.
Arash HatefiDepartment of Pharmaceutics, Rutgers University, Piscataway, NJ, USA. Electronic address: ahatefi@pharmacy.rutgers.edu.
Rutgers, The State University of New Jersey · USUniversity of Pennsylvania · USImaging Center · USStanford University · US

Funding

TRANSCRIPTIONAL PROFILINGP30CA072720 · NCI · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI Chang S Chan · 1997 to 2026
$94.5M
Stem Cell-based Platform for Targeted Enzyme/Prodrug Therapy of Recurrent Ovarian CancerR01CA251438 · NCI · RUTGERS, THE STATE UNIV OF N.J. · PI HATEFI, ARASH · 2021 to 2025
$1.9M
A Nanotechnology Platform for Suicide Gene Therapy of Recurring Ovarian CancerR01CA175318 · NCI · RUTGERS, THE STATE UNIV OF N.J. · PI HATEFI, ARASH · 2015 to 2019
$1.8M
NCI NIH HHS P30 CA072720NCI NIH HHS R01 CA175318NCI NIH HHS R01 CA251438
6 · The paper itself

Abstract

Ovarian cancer has the highest mortality rate among all gynecologic malignancies. HER2

Indexed as

Lung NeoplasmsOvarian NeoplasmsAnimalsFemaleGadoliniumHumansMagnetic Resonance ImagingMiceMice, SCIDPositron Emission Tomography Computed TomographyGadoliniumContrast agentGadoliniumHER2 imagingLung metastasisMRIOvarian cancer

Identifiers

PMID34284047
PMCPMC8440463
OpenAlexW3186348701

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.