Evidence map›Paper›PMID 34284034›Full record

ArticleThe Journal of pediatrics2021

Computational Fluid Dynamic Modeling Reveals Nonlinear Airway Stress during Trachea Development.

Eric C Mason, Zhenxing Wu, Sam McGhee, Jennifer Markley, Maria Koenigs, Amanda Onwuka, Tendy Chiang, Kai Zhao

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of pediatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Eric C MasonDepartment of Otolaryngology-Head and Neck Surgery, The Ohio State University, Columbus, OH.
Zhenxing WuDepartment of Otolaryngology-Head and Neck Surgery, The Ohio State University, Columbus, OH.
Sam McGheeDepartment of Otolaryngology-Head and Neck Surgery, The Ohio State University, Columbus, OH.
Jennifer MarkleyDepartment of Otolaryngology-Head and Neck Surgery, The Ohio State University, Columbus, OH.
Maria KoenigsDepartment of Otolaryngology-Head and Neck Surgery, The Ohio State University, Columbus, OH.
Amanda OnwukaCenter for Surgical Outcomes Research, The Research Institute at Nationwide Children's Hospital, Columbus, OH.
Tendy ChiangDepartment of Otolaryngology-Head and Neck Surgery, The Ohio State University, Columbus, OH; Department of Otolaryngology, Nationwide Children's Hospital, Columbus, OH; Center for Regenerative Medicine, The Research Institute at Nationwide Children's Hospital, Columbus, OH.
Kai ZhaoDepartment of Otolaryngology-Head and Neck Surgery, The Ohio State University, Columbus, OH. Electronic address: zhao.1949@osu.edu.

Funding

Objective evaluation of conductive olfactory losses & nasal obstruction symptomsR01DC013626 · NIDCD · OHIO STATE UNIVERSITY · PI ZHAO, KAI · 2015 to 2018
$1.6M
Mechanisms of regeneration in tissue engineered tracheal graftsK08HL138460 · NHLBI · RESEARCH INST NATIONWIDE CHILDREN'S HOSP · PI CHIANG, TENDY · 2017 to 2021
$788k
Endoscopic nasal sinus surgery simulator to optimize treatment outcomeR21DC017530 · NIDCD · OHIO STATE UNIVERSITY · PI ZHAO, KAI · 2019 to 2020
$442k
NHLBI NIH HHS K08 HL138460NIDCD NIH HHS R01 DC013626NIDCD NIH HHS R21 DC017530
6 · The paper itself

Abstract

Normative trachea dimensions and aerodynamic information during development was collected to establish clinical benchmarks and showed that airway development seems to outpace respiratory demands. Infants and toddlers' trachea exhibit higher aerodynamic stress that significantly decreases by teenage years. This implies large airway pathology in younger children may have a more substantial clinical impact.

Indexed as

Computer SimulationHydrodynamicsAdolescentAirway ResistanceChildChild, PreschoolCohort StudiesFemaleHumansInfantMaleStress, PhysiologicalTracheaairflow metricsairway modelingpediatric airway physiology

Identifiers

PMID34284034
PMCPMC8551055

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.