Evidence map›Paper›PMID 34283371›Full record

ReviewInflammopharmacology2021

Role of Myeloid-derived suppressor cell (MDSC) in autoimmunity and its potential as a therapeutic target.

Ehsan Nourbakhsh, Ali Mohammadi, Mohammad Salemizadeh Parizi, Atena Mansouri, Farnoosh Ebrahimzadeh

Abstract readReview
PubMed Publisher
In one paragraph

Review in Inflammopharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 26 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 1 country.

Ehsan NourbakhshDoctor of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Ali MohammadiBachelor of Cell Biology and Molecular-Genetics, Marand Azad University, Marand, Iran.
Mohammad Salemizadeh PariziDepartment of Electrical Engineering, University of Tehran, Tehran, Iran.
Atena MansouriDepartment of Biology, Science and Research Branch, Islamic Azad University, Tehran, Iran.
Farnoosh EbrahimzadehInternist, Assistant Professor, Department of Internal Medicine, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran. ebrahimzadehf@mums.ac.ir.ORCID http://orcid.org/0000-0002-6834-3881
Islamic Azad University of Marand · IRIslamic Azad University, Science and Research Branch · IRMashhad University of Medical Sciences · IRShahid Beheshti University of Medical Sciences · IRUniversity of Tehran · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Myeloid suppressor cells (MDSCs) are an important class of immune-regulating cells that can suppress T cell function. Most of our knowledge about the function of MDSC comes from studies of cancer models. Recent studies, however, have greatly contributed to the description of MDSC involvement in autoimmune diseases. They are known as a cell population that may negatively affect immune responses by regulating the function of CD4

Indexed as

AnimalsAutoimmune DiseasesAutoimmunityCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesHumansMyeloid-Derived Suppressor CellsAutoimmunityDiabetesMDSCmultiple sclerosisRheumatoid arthritis

Identifiers

PMID34283371
OpenAlexW3185422181

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.