ArticleCancers2021
Vascular Involvement in Thymic Epithelial Tumors: Surgical and Oncological Outcomes.
Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.
- Thymomas With Intravascular and Intracardiac Growth.Frontiers in oncology · 2022Pooled it
- A single-center external validation and refinement of the 9th TNM staging system for thymic epithelial tumors: a scheme enhancing prognostic stratification.Frontiers in oncology · 2026Article
- Advanced thymic epithelial tumour resection: vascular resection and reconstruction strategy.Journal of thoracic disease · 2025Article
- Role of Cine-Magnetic Resonance Imaging in the Assessment of Mediastinal Masses with Uncertain/Equivocal Findings from Pre-Operative Computed Tomography Scanning.Diagnostics (Basel, Switzerland) · 2024Article
- Thymus Surgery Prospectives and Perspectives in Myasthenia Gravis.Journal of personalized medicine · 2024Review
- Long term outcome of complex surgical resection and reconstruction for rare thoracic cancers.Tumori · 2023Article
- Significance of the Surgical Treatment with Lymph Node Dissection for Neuroendocrine Tumors of Thymus.Cancers · 2023Article
- Article
- Real-world clinicopathological features and outcome of thymic neuroendocrine tumors: a retrospective single-institution analysis.Orphanet journal of rare diseases · 2022Article
Corrections and comments
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Authors and funding
12 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe involvement of mediastinal great vessels is common in advanced stage thymic tumors, which makes their surgical resection challenging. Moreover, the impact of vascular involvement on the oncological prognosis is still unclear. The aim of this study is to investigate the surgical and oncological outcomes and the impact of vascular involvement in a population of patients operated for advanced stage thymic tumors.
methodsA retrospective analysis on four hundred and sixty-five patients undergoing resection for advanced stage (Masaoka III-IV) thymic tumors in a single high-volume center was performed. One hundred forty-four patients met the inclusion criteria and were eligible for the study. Patients were divided in two groups according to the presence or absence of vascular involvement.
resultsthe two groups did not differ for the baseline characteristics and showed comparable surgical outcomes. Vascular involvement was not associated with worse overall survival but with an increased recurrence rate (
conclusionsresection of thymic tumors with vascular involvement can be performed with optimal surgical results in a high volume center. From the oncological point of view, the involvement of the great vessels seems to be associated with a higher recurrence rate without affecting long-term survival.
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