ArticlemSystems2021
Accessory Genomic Epidemiology of Cocirculating Acinetobacter baumannii Clones.
Article in mSystems, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed.
- Comparative Population Genomics and Machine Learning Reveal a Distinct Regional Genomic Fingerprint of Middle EasternMicroorganisms · 2026Article
- Global multi-host genomic epidemiology of Acinetobacter baumannii reveals transmission at one health interfaces.Nature communications · 2026Article
- Exploratory Insights on Epidemiology, Genomic Features and Pangenome Analysis of NDM-1-Positive Carbapenem-ResistantAntibiotics (Basel, Switzerland) · 2026Article
- Genome-wide co-occurrence patterns link mobile genetic elements, antimicrobial resistance and defense systems in Pseudomonas aeruginosa.BMC genomics · 2026Article
- Genomic epidemiology reveals statewide dispersal of clinical Shiga toxin-producingMicrobiology spectrum · 2026Article
- Outbreak investigation of extensively drug-resistantFrontiers in cellular and infection microbiology · 2026Article
- Article
- Comparative genomics of carbapenem-resistantMicrobiology spectrum · 2025Article
- Review
- Genomic epidemiology reveals antibiotic resistance transfer and polyclonal dissemination ofAntimicrobial agents and chemotherapy · 2025Article
- Variants of β-lactamase-encoding genes are disseminated by multiple genetically distinct lineages of bloodstream Escherichia coli.Communications medicine · 2025Article
- Targeting Acinetobacter baumannii resistance-nodulation-division efflux pump transcriptional regulators to combat antimicrobial resistance.npj antimicrobials and resistance · 2025Review
- Average nucleotide identity-basedmSystems · 2024Article
- Article
- Evolutionary dynamics of the accessory genomes ofmSphere · 2024Article
- Genome sequencing unveilsmSystems · 2024Article
- Article
- Article
- Gram-negative ESKAPE bacteria bloodstream infections in patients during the COVID-19 pandemic.PeerJ · 2023Article
- Pandrug-resistantFrontiers in cellular and infection microbiology · 2023Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
Acinetobacter baumannii has become one of the most important multidrug-resistant nosocomial pathogens all over the world. Nonetheless, very little is known about the diversity of A. baumannii lineages coexisting in hospital settings. Here, using whole-genome sequencing, epidemiological data, and antimicrobial susceptibility tests, we uncover the transmission dynamics of extensive and multidrug-resistant A. baumannii in a tertiary hospital over a decade. Our core genome phylogeny of almost 300 genomes suggests that there were several introductions of lineages from international clone 2 into the hospital. The molecular dating analysis shows that these introductions happened in 2006, 2007, and 2013. Furthermore, using the accessory genome, we show that these lineages were extensively disseminated across many wards in the hospital. Our results demonstrate that accessory genome variation can be a very powerful tool for conducting genomic epidemiology. We anticipate future studies employing the accessory genome along with the core genome as a powerful phylogenomic strategy to track bacterial transmissions over very short microevolutionary scales.
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