Evidence map›Paper›PMID 34282937›Full record

ArticlemSystems2021

Differential Analysis of Longitudinal Methicillin-Resistant Staphylococcus aureus Colonization in Relation to Microbial Shifts in the Nasal Microbiome of Neonatal Piglets.

Shriram Patel, Abel A Vlasblom, Koen M Verstappen, Aldert L Zomer, Ad C Fluit, Malbert R C Rogers, Jaap A Wagenaar, Marcus J Claesson, Birgitta Duim

Open access · goldAbstract read
In one paragraph

Article in mSystems, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
  3. iScience · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Safety Evaluation of an Intranasally Applied Cocktail ofAnimals : an open access journal from MDPI · 2023
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Shriram Patel *APC Microbiome Ireland, University College Corkgrid.7872.a, Cork, Ireland.
Abel A Vlasblom *Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, the Netherlands.
Koen M VerstappenDepartment of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, the Netherlands.
Aldert L ZomerDepartment of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, the Netherlands.
Ad C FluitDepartment of Medical Microbiology, University Medical Centre Utrecht, Utrecht, the Netherlands.
Malbert R C RogersDepartment of Medical Microbiology, University Medical Centre Utrecht, Utrecht, the Netherlands.
Jaap A WagenaarDepartment of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, the Netherlands.
Marcus J ClaessonAPC Microbiome Ireland, University College Corkgrid.7872.a, Cork, Ireland.
Birgitta DuimDepartment of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, the Netherlands.
Utrecht University · NLUniversity College Cork · IEUniversity Medical Center Utrecht · NL

Funding

Joint Programming Initiative on Antimicrobial Resistance (JPIAMR) 50-52900-98-043Science Foundation Ireland (SFI) SFI/12/RC/2273_P2
6 · The paper itself

Abstract

Methicillin-resistant Staphylococcus aureus (MRSA) is an important human pathogen and often colonizes pigs. To lower the risk of MRSA transmission to humans, a reduction of MRSA prevalence and/or load in pig farms is needed. The nasal microbiome contains commensal species that may protect against MRSA colonization and may be used to develop competitive exclusion strategies. To obtain a comprehensive understanding of the species that compete with MRSA in the developing porcine nasal microbiome, and the moment of MRSA colonization, we analyzed nasal swabs from piglets in two litters. The swabs were taken longitudinally, starting directly after birth until 6 weeks. Both 16S rRNA and

Indexed as

colonizationmicrobial shiftsMRSAporcine nasal microbiomeStaphylococcus aureus

Identifiers

PMID34282937
PMCPMC8407314
OpenAlexW3185570417

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.