ArticleThe journals of gerontology. Series A, Biological sciences and medical sciences2021
Longitudinal Associations Between Discrimination, Neighborhood Social Cohesion, and Telomere Length: The Multi-Ethnic Study of Atherosclerosis.
Article in The journals of gerontology. Series A, Biological sciences and medical sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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16 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.
- Perceived Discrimination and Immunological Aging: A Systematic Review of Cellular and Molecular Markers.Biopsychosocial science and medicinePooled it
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- Living in historically redlined neighborhoods and biological aging among older adults.The journals of gerontology. Series A, Biological sciences and medical sciences · 2025Article
- Correlates of longitudinal patterns of racial discrimination in midlife and older Black adults: Evidence from the health and retirement study.Social science & medicine (1982) · 2025Article
- A Society-to-Cells approach to evaluating multilevel and interrelated drivers of breast cancer disparities in Black women.NPJ breast cancer · 2025Review
- Spouses' Individual and Shared Cumulative Risk: Implications for Functional Health and Longevity in Older Adulthood.American journal of preventive medicine · 2025Article
- Neighborhood social cohesion and Alzheimer's disease dementia risk in South Asians in the United States.Alzheimer's & dementia. Behavior & socioeconomics of aging · 2025Article
- Structural and social determinants of health: The multi-ethnic study of atherosclerosis.PloS one · 2024Article
- Structural and social determinants of health: The multi-ethnic study of atherosclerosis.PloS one · 2024Article
- Examining the Cross-sectional Association Between Neighborhood Conditions, Discrimination, and Telomere Length in a Predominantly African American Sample.Journal of racial and ethnic health disparities · 2023Article
- Self-reported experiences of discrimination and incident dementia.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2023Article
- Community social environments and cigarette smoking.SSM - population health · 2022Article
- Structural Racial Discrimination and Structural Resilience: Measurement Precedes Change.The journals of gerontology. Series A, Biological sciences and medical sciences · 2022Article
- Promoting Health Equity Across the Life Span.The journals of gerontology. Series A, Biological sciences and medical sciences · 2022Article
- Defining the Exposome Using Popular Education and Concept Mapping With Communities in Atlanta, Georgia.Frontiers in public health · 2022Article
- Earth Dreams: Reimagining ARPA for Health of People, Places and Planet.International journal of environmental research and public health · 2021Article
Corrections and comments
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Authors and funding
6 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWe aimed to examine if neighborhood social cohesion moderated longitudinal associations between baseline reports of discrimination and 10-year changes in Leukocyte Telomere Length (LTL).
methodsData are from the Multi-Ethnic Study of Atherosclerosis (MESA; N=1,064; age range 45-84 years). Baseline discrimination was measured using the Major Experiences of Discrimination Scale (MDS; none, 1 domain, ≥2 domains) and the Experiences of Discrimination Scale (EDS; none, moderate, high). Neighborhood social cohesion at baseline was assessed via a community survey within census tract defined neighborhoods. 10-year change in LTL was defined as Regression to the Mean corrected 10-year difference in the ratio of telomeric DNA to a single copy gene (T/S).
resultsIn linear mixed effects models, we found that neighborhood social cohesion modified the effect of baseline reports of MDS on 10-year changes in LTL, independent of sociodemographic characteristics, health behaviors, and health conditions (p(χ 2)=0.01). Among those residing in neighborhoods with low social cohesion, experiencing major discrimination in ≥2 domains was associated with faster LTL attrition over 10-years, compared to reporting no discrimination (β=-0.03; 95% CI: -0.06, -0.003). We found no main associations for either discrimination measure and no interaction between EDS and neighborhood social cohesion.
conclusionsResults indicate that neighborhood social cohesion is an important dimension of the neighborhood context that may moderate the impact of major experiences of discrimination on telomere length attrition. These findings help advance our understanding of the integral role that neighborhood environments play in attenuating the effect of discrimination on accelerated cell aging.
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