Evidence map›Paper›PMID 34282779›Full record

ArticleCancers2021

Serum HPV16 E7 Oncoprotein Is a Recurrence Marker of Oropharyngeal Squamous Cell Carcinomas.

Lucia Oton-Gonzalez, John Charles Rotondo, Carmen Lanzillotti, Elisa Mazzoni, Ilaria Bononi, Maria Rosa Iaquinta, Luca Cerritelli, Nicola Malagutti, Andrea Ciorba, Chiara Bianchini and 3 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Detection of antibody subclasses IgA, IgM and IgG against HPV L1 in HPV-positive oropharyngeal squamous cell carcinoma patients: a pilot study.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2024
    Observational
  3. Article
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Lucia Oton-GonzalezDepartment of Medical Sciences, University of Ferrara, 44121 Ferrara, Italy.ORCID 0000-0002-8515-6754
John Charles RotondoDepartment of Medical Sciences, University of Ferrara, 44121 Ferrara, Italy.ORCID 0000-0001-5179-1525
Carmen LanzillottiDepartment of Medical Sciences, University of Ferrara, 44121 Ferrara, Italy.
Elisa MazzoniDepartment of Medical Sciences, University of Ferrara, 44121 Ferrara, Italy.
Ilaria BononiDepartment of Translational Medicine and for Romagna, University of Ferrara, 44121 Ferrara, Italy.
Maria Rosa IaquintaDepartment of Medical Sciences, University of Ferrara, 44121 Ferrara, Italy.ORCID 0000-0003-3242-859X
Luca CerritelliENT Unit, Department of Neuroscience and Rehabilitation, University Hospital of Ferrara, 44121 Ferrara, Italy.
Nicola MalaguttiENT Unit, Department of Neuroscience and Rehabilitation, University Hospital of Ferrara, 44121 Ferrara, Italy.
Andrea CiorbaENT Unit, Department of Neuroscience and Rehabilitation, University Hospital of Ferrara, 44121 Ferrara, Italy.ORCID 0000-0003-3455-2295
Chiara BianchiniENT Unit, Department of Neuroscience and Rehabilitation, University Hospital of Ferrara, 44121 Ferrara, Italy.
Stefano PelucchiENT Unit, Department of Neuroscience and Rehabilitation, University Hospital of Ferrara, 44121 Ferrara, Italy.
Mauro TognonDepartment of Medical Sciences, University of Ferrara, 44121 Ferrara, Italy.
Fernanda MartiniDepartment of Medical Sciences, University of Ferrara, 44121 Ferrara, Italy.
University of Ferrara · IT

Funding

Associazione Italiana per la Ricerca sul Cancro 21617Associazione Italiana per la Ricerca sul Cancro MFAG 21956Università degli Studi di Ferrara FAR Projects
6 · The paper itself

Abstract

Despite improved prognosis for many HPV-positive head and neck squamous cell carcinomas (HNSCCs), some cases are still marked by recurrence and metastasis. Our study aimed to identify novel biomarkers for patient stratification. Classical HPV markers: HPV-DNA, p16 and HPV mRNA expression were studied in HNSCC (

Indexed as

E7 oncoproteinELISAHPV antibodiesHPV DNAhuman papillomavirusoropharyngeal squamous cell carcinomapatient stratificationtreatment de-escalation

Identifiers

PMID34282779
PMCPMC8268104
OpenAlexW3177999054

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.