Evidence map›Paper›PMID 34282756›Full record

ArticleCancers2021

Physical Comorbidities and Depression in Recent and Long-Term Adult Cancer Survivors: NHANES 2007-2018.

Dafina Petrova, Andrés Catena, Miguel Rodríguez-Barranco, Daniel Redondo-Sánchez, Eloísa Bayo-Lozano, Rocio Garcia-Retamero, José-Juan Jiménez-Moleón, María-José Sánchez

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 41 citations in OpenAlex.

  1. Article
  2. Allostatic Load and Healthcare Access Among Stroke Survivors.Journal of racial and ethnic health disparities · 2026
    Article
  3. Article
  4. Article
  5. Age at menopause and multimorbidity in postmenopausal women.Przeglad menopauzalny = Menopause review · 2025
    Article
  6. Article
  7. Article
  8. Qigong in the care of breast cancer survivors with diabetes.Asia-Pacific journal of oncology nursing · 2024
    Article
  9. Article
  10. Article
  11. Navigating the Intersection of Technology and Depression Precision Medicine.Advances in experimental medicine and biology · 2024
    Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Empirical Dietary Patterns Associated with Food Insecurity in U.S. Cancer Survivors: NHANES 1999-2018.International journal of environmental research and public health · 2022
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Dafina PetrovaCIBER of Epidemiology and Public Health (CIBERESP), 28029 Madrid, Spain.ORCID 0000-0002-0346-6776
Andrés CatenaMind, Brain and Behavior Research Center, University of Granada, 18071 Granada, Spain.
Miguel Rodríguez-BarrancoCIBER of Epidemiology and Public Health (CIBERESP), 28029 Madrid, Spain.ORCID 0000-0002-9972-9779
Daniel Redondo-SánchezCIBER of Epidemiology and Public Health (CIBERESP), 28029 Madrid, Spain.ORCID 0000-0001-9986-915X
Eloísa Bayo-LozanoDepartment of Radiation Oncology, University Hospital Virgen Macarena, 49009 Seville, Spain.
Rocio Garcia-RetameroMind, Brain and Behavior Research Center, University of Granada, 18071 Granada, Spain.
José-Juan Jiménez-MoleónCIBER of Epidemiology and Public Health (CIBERESP), 28029 Madrid, Spain.ORCID 0000-0001-7917-6145
María-José SánchezCIBER of Epidemiology and Public Health (CIBERESP), 28029 Madrid, Spain.ORCID 0000-0003-4817-0757
Universidad de Granada · ESInstituto de Investigación Biosanitaria de Granada · ESHospital Universitario Virgen Macarena · ES

Funding

Health Institute Carlos III CD19/00203
6 · The paper itself

Abstract

Many adult cancer patients present one or more physical comorbidities. Besides interfering with treatment and prognosis, physical comorbidities could also increase the already heightened psychological risk of cancer patients. To test this possibility, we investigated the relationship between physical comorbidities with depression symptoms in a sample of 2073 adult cancer survivors drawn from the nationally representative National Health and Nutrition Examination Survey (NHANES) (2007-2018) in the U.S. Based on information regarding 16 chronic conditions, the number of comorbidities diagnosed before and after the cancer diagnosis was calculated. The number of comorbidities present at the moment of cancer diagnosis was significantly related to depression risk in recent but not in long-term survivors. Recent survivors who suffered multimorbidity had 3.48 (95% CI 1.26-9.55) times the odds of reporting significant depressive symptoms up to 5 years after the cancer diagnosis. The effect of comorbidities was strongest among survivors of breast cancer. The comorbidities with strongest influence on depression risk were stroke, kidney disease, hypertension, obesity, asthma, and arthritis. Information about comorbidities is usually readily available and could be useful in streamlining depression screening or targeting prevention efforts in cancer patients and survivors. A multidimensional model of the interaction between cancer and other physical comorbidities on mental health is proposed.

Indexed as

cancercancer survivorscomorbiditydepressionmental health

Identifiers

PMID34282756
PMCPMC8268421
OpenAlexW3182745799

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.