Evidence map›Paper›PMID 34282613›Full record

ArticleJournal of the American Chemical Society2021

Asymmetric Radical Process for General Synthesis of Chiral Heteroaryl Cyclopropanes.

Xiaoxu Wang, Jing Ke, Yiling Zhu, Arghya Deb, Yijie Xu, X Peter Zhang

Open access · greenAbstract read
In one paragraph

Article in Journal of the American Chemical Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
6.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 75 citations in OpenAlex.

  1. Photogenerated Oxetanes as a Gateway to Uphill Cyclopropanation.Angewandte Chemie (International ed. in English) · 2026
    Article
  2. Quaternary Carbons from Amines and Acids.Journal of the American Chemical Society · 2026
    Article
  3. Article
  4. Bimolecular Homolytic Substitution (SACS central science · 2025
    Review
  5. Trisubstituted Alkenes as Valuable Building Blocks.Molecules (Basel, Switzerland) · 2025
    Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Late-Stage C(Journal of the American Chemical Society · 2023
    Article
  16. Article
  17. Review
  18. Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Xiaoxu WangDepartment of Chemistry, Merkert Chemistry Center, Boston College, Chestnut Hill, Massachusetts 02467, United States.ORCID 0000-0003-0444-6950
Jing KeDepartment of Chemistry, Merkert Chemistry Center, Boston College, Chestnut Hill, Massachusetts 02467, United States.ORCID 0000-0001-8006-6541
Yiling ZhuDepartment of Chemistry, Merkert Chemistry Center, Boston College, Chestnut Hill, Massachusetts 02467, United States.
Arghya DebDepartment of Chemistry, Merkert Chemistry Center, Boston College, Chestnut Hill, Massachusetts 02467, United States.
Yijie XuDepartment of Chemistry, Merkert Chemistry Center, Boston College, Chestnut Hill, Massachusetts 02467, United States.ORCID 0000-0002-6433-0610
X Peter ZhangDepartment of Chemistry, Merkert Chemistry Center, Boston College, Chestnut Hill, Massachusetts 02467, United States.ORCID 0000-0001-7574-8409
Boston College · US

Funding

Catalytic Processes for Stereoselective Radical Cyclization ReactionsR01GM102554 · NIGMS · BOSTON COLLEGE · PI ZHANG, X. PETER · 2015 to 2024
$3.4M
NIGMS NIH HHS R01 GM102554
6 · The paper itself

Abstract

A highly efficient catalytic method has been developed for asymmetric radical cyclopropanation of alkenes with in situ-generated α-heteroaryldiazomethanes via Co(II)-based metalloradical catalysis (MRC). Through fine-tuning the cavity-like environments of newly-synthesized

Indexed as

CatalysisCobaltCoordination ComplexesCyclopropanesFree RadicalsMolecular StructureStereoisomerismCobaltCoordination ComplexesCyclopropanesFree Radicals

Identifiers

PMID34282613
PMCPMC8399893
OpenAlexW3184780133

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.