Evidence map›Paper›PMID 34282569›Full record

SynthesisObesity surgery2021

Transversus Abdominis Plane Block Versus Intraperitoneal Local Anesthetics in Bariatric Surgery: A Systematic Review and Network Meta-analysis.

Sook Hui Chaw, Yoke Lin Lo, Siew-Li Goh, Chao Chia Cheong, Wei Keang Tan, Pui San Loh, Lai Fen Wong, Ina Ismiarti Shariffuddin

Abstract readSystematic ReviewNetwork Meta-Analysis
PubMed Publisher
In one paragraph

Synthesis in Obesity surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 5 pooled it
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 5 syntheses or guidelines pooled it, 33 citations in OpenAlex.

  1. Pooled it
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  6. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Sook Hui ChawDepartment of Anesthesiology, Faculty of Medicine, University of Malaya, 50603, Kuala Lumpur, Malaysia.
Yoke Lin LoDepartment of Pharmacy Practice, School of Pharmacy, International Medical University, 57000, Kuala Lumpur, Malaysia.
Siew-Li GohSports and Exercise Medicine Research and Education Group, Faculty of Medicine, University of Malaya, 50603, Kuala Lumpur, Malaysia.
Chao Chia CheongDepartment of Anesthesiology, Faculty of Medicine, University of Malaya, 50603, Kuala Lumpur, Malaysia.
Wei Keang TanDepartment of Anesthesiology, Faculty of Medicine, University of Malaya, 50603, Kuala Lumpur, Malaysia.
Pui San LohDepartment of Anesthesiology, Faculty of Medicine, University of Malaya, 50603, Kuala Lumpur, Malaysia.
Lai Fen WongDepartment of Surgery, Faculty of Medicine, University of Malaya, 50603, Kuala Lumpur, Malaysia.
Ina Ismiarti ShariffuddinDepartment of Anesthesiology, Faculty of Medicine, University of Malaya, 50603, Kuala Lumpur, Malaysia. iishariffuddin@gmail.com.ORCID http://orcid.org/0000-0002-7528-9027
University of Malaya · MYIMU University · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTransversus abdominis plane (TAP) block and intraperitoneal local anesthetics (IPLA) are widely investigated techniques that potentially improve analgesia after bariatric surgery. The analgesic efficacy of TAP block has been shown in previous studies, but the performance of TAP block can be difficult in patients with obesity. We performed a systematic review and meta-analysis to compare the analgesic efficacy of TAP block and IPLA. An alternative technique is useful in clinical setting when TAP block is not feasible.

methodsWe searched PubMed, Embase, and CENTRAL from inception until August 2020 for randomized controlled trials comparing both techniques. The primary outcome was cumulative morphine consumption at 24 h. Secondary pain-related outcomes included pain score at rest and on movement at 2, 6, 12, and 24 h; postoperative nausea and vomiting; and length of hospital stay.

resultsWe included 23 studies with a total of 2,178 patients. TAP block is superior to control in reducing opioid consumption at 24 h, improving pain scores at all the time points and postoperative nausea and vomiting. The cumulative opioid consumption at 24 h for IPLA is less than control, while the indirect comparison between IPLA with PSI and control showed a significant reduction in pain scores at rest, at 2 h, and on movement at 12 h, and 24 h postoperatively.

conclusionsTransversus abdominis plane block is effective for reducing pain intensity and has superior opioid-sparing effect compared to control. Current evidence is insufficient to show an equivalent analgesic benefit of IPLA to TAP block.

Indexed as

Bariatric SurgeryObesity, MorbidAbdominal MusclesAnalgesics, OpioidAnesthetics, LocalHumansPostoperative PainAnalgesics, OpioidAnesthetics, LocalLocal anestheticsMultimodal analgesiaNetwork meta-analysisPostoperative painPROSPERO Registration: CRD 42019137038Regional analgesiaSystematic review

Identifiers

PMID34282569
OpenAlexW3183754694

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.