Evidence map›Paper›PMID 34282553›Full record

ArticleJournal of endocrinological investigation2022

Total and free vitamin D metabolites in patients with primary hyperparathyroidism.

L Meng, C Su, S A Shapses, X Wang

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of endocrinological investigation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
  6. Critical Role for 24-Hydroxylation in Homeostatic Regulation of Vitamin D Metabolism.The Journal of clinical endocrinology and metabolism · 2025 · on this map
    Article
  7. Review
  8. Critical Role for 24-Hydroxylation in Homeostatic Regulation of Vitamin D Metabolism.medRxiv : the preprint server for health sciences · 2024
    Article
  9. Parathyroid diseases and metabolic syndrome.Journal of endocrinological investigation · 2023
    Review
  10. Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

L MengDepartment of Nutritional Sciences, Rutgers University, New Brunswick, NJ, 08901, USA.
C SuGraduate School of Biomedical Science, Rutgers University, Piscataway, NJ, 08854, USA.
S A ShapsesDepartment of Nutritional Sciences, Rutgers University, New Brunswick, NJ, 08901, USA.
X WangDivision of Endocrinology, Department of Medicine, Rutgers University-Robert Wood Johnson Medical School, New Brunswick, NJ, 08093, USA. wangx9@rwjms.rutgers.edu.
Rutgers, The State University of New Jersey · USJohnson University · US

Funding

NUTRITIONAL REGULATION OF BONE TURNOVERR01AG012161 · NIA · RUTGERS THE ST UNIV OF NJ NEW BRUNSWICK · PI SHAPSES, SUE AMY · 2000 to 2014
$3.4M
NUTRITIONAL REGULATION OF BONE TURNOVERR29AG012161 · NIA · RUTGERS THE ST UNIV OF NJ NEW BRUNSWICK · PI SHAPSES, SUE AMY · 1994 to 1998
–
NIA NIH HHS NIH-AG12161NIFA-USDA NJAES-0153866
6 · The paper itself

Abstract

purposeTo evaluate total and free vitamin D metabolites and hormone-to-prohormone [1,25(OH)

methodsThirty female patients with primary hyperparathyroidism (PHPT) and 30 age and body mass index (BMI) matched healthy controls were enrolled. Serum levels of calcium, intact parathyroid hormone (iPTH), vitamin D binding protein (DBP), albumin, total 25(OH)D and 1,25(OH)

resultsCompared to the control subject, patients with PHPT had a lower total 25(OH)D and DBP levels (p < 0.001). The serum concentration of free 25(OH)D and total 1,25(OH)

conclusionPatients with PHPT had significantly higher free 1,25(OH)

Indexed as

Hyperparathyroidism, PrimaryVitamin DVitamin D DeficiencyAdultBody Mass IndexCalciumCorrelation of DataFemaleHumansParathyroid HormonePatient SelectionVitamin D-Binding ProteinCalciumGC protein, humanParathyroid HormoneVitamin DVitamin D-Binding Protein1,25-Dihydroxyvitamin DHyperparathyroidismParathyroid hormoneVitamin DVitamin D activation ratio

Identifiers

PMID34282553
OpenAlexW3186901382

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.