ArticleNature immunology2021
BATF regulates progenitor to cytolytic effector CD8
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Article in Nature immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 133 papers.
0numbers the graph read from it
0cells of the map it votes in
133citing papers in PubMed
9.5field-weighted citation impact, top 1% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
133 citing papers in PubMed, 179 citations in OpenAlex.
- A T-cell exhaustion-related signature for predicting response to immunotherapy among patients with lung adenocarcinoma.Translational lung cancer research · 2026Article
- Article
- Targeting Regnase-1 in B7-H3-CAR T cells reprograms the tumor microenvironment and enhances antitumor efficacy for osteosarcoma.Cell reports. Medicine · 2026Article
- BATF3 regulates differentiation of CD8Life science alliance · 2026Article
- Single-cell gain-of-function mapping reveals latent regulatory programs governing CD8Research square · 2026Article
- Hallmarks and correlates of effective adoptive cell immunotherapy for cancer.Nature reviews. Immunology · 2026Review
- Enforced BATF expression via clinically approved LNPs enhances adoptive T-cell therapies.Blood science (Baltimore, Md.) · 2026Article
- Proteostasis sustains T cell differentiation potential and tumor-infiltrating lymphocyte function.Cell · 2026Article
- Krüppel-like factors 2 and 3 regulate T cell exhaustion by directing T cell residency and migration.Immunity · 2026Article
- T cell adaptation in chronic infections and tumors.Cellular & molecular immunology · 2026Review
- ZFP148 is a transcriptional repressor of cytolytic effector CD8Nature immunology · 2026Article
- Article
- Integrative multi-omics analysis reveals an 11-gene malignant-myeloid interaction signature and identifies TPST1 as a potential regulator of immunosuppressive microenvironment in glioma.Discover oncology · 2026Article
- Functional Type I and Type II interferon crosstalk restricts progenitor exhausted CD8 T cells through spatial exclusion and checkpoint enforcement.bioRxiv : the preprint server for biology · 2026Article
- Stem-like memory-T maintenance and differentiation into tissue-resident T cells sustain chronic graft-versus-host disease in mice.Nature communications · 2026Article
- Proteostasis sustains T cell differentiation potential and tumor-infiltrating lymphocyte function.bioRxiv : the preprint server for biology · 2026Article
- Regulators of CD8Nature reviews. Immunology · 2026Review
- T Cell Exhaustion in Hepatocellular Carcinoma: A Substantial Barrier in Immunotherapy.Journal of cellular and molecular medicine · 2026Review
- Single-Cell Clonal Lineage Tracing Identifies the Transcriptional Program Controlling the Cell-Fate Decisions by Neoantigen-Specific CD8+ T Cells.Cancer immunology research · 2026Article
- Epigenetic regulation of T cell exhaustion in cancer.Nature reviews. Cancer · 2026Review
73 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 1 country.
Yao ChenBlood Research Institute, Versiti, Milwaukee, WI, USA.
Ryan A ZanderBlood Research Institute, Versiti, Milwaukee, WI, USA.
Xiaopeng WuBlood Research Institute, Versiti, Milwaukee, WI, USA.
David M SchauderBlood Research Institute, Versiti, Milwaukee, WI, USA.
Moujtaba Y KasmaniBlood Research Institute, Versiti, Milwaukee, WI, USA.ORCID http://orcid.org/0000-0002-5753-5335
Jian ShenBlood Research Institute, Versiti, Milwaukee, WI, USA.ORCID http://orcid.org/0000-0001-8398-2318
Shikan ZhengBlood Research Institute, Versiti, Milwaukee, WI, USA.
Robert BurnsBlood Research Institute, Versiti, Milwaukee, WI, USA.
Elizabeth J TaparowskyDepartment of Biological Sciences and Purdue University Center for Cancer Research, Purdue University, West Lafayette, IN, USA.ORCID http://orcid.org/0000-0002-4677-9369
Weiguo CuiBlood Research Institute, Versiti, Milwaukee, WI, USA. weiguo.cui@bcw.edu.ORCID http://orcid.org/0000-0003-1562-9218
Medical College of Wisconsin · USVersiti Blood Center of Wisconsin · USPurdue University West Lafayette · US
Funding
Medical Scientist Training ProgramT32GM080202 · NIGMS · MEDICAL COLLEGE OF WISCONSIN · PI BARBIERI, JOSEPH T, SALZMAN, NITA H · 2010 to 2024
$5.7MPhenotypic, Functional and Transcriptional Heterogeneity in T Cell ExhaustionR01AI148403 · NIAID · VERSITI WISCONSIN, INC. · PI WEIGUO CUI · 2020 to 2026
$3.1MThe Cellular and Transcriptional Control of CD8 T Cell Functional Adaptation to Chronic VirusesR01AI125741 · NIAID · VERSITI WISCONSIN, INC. · PI CUI, WEIGUO · 2016 to 2020
$2.1MDefining the transcriptional, phenotypic, and functional heterogeneity of virus-specific CD4 T cells during chronic viral infectionR00AI153537 · NIAID · UNIVERSITY OF IOWA · PI ZANDER, RYAN · 2022 to 2023
$498kDefining the transcriptional, phenotypic, and functional heterogeneity of virus-specific CD4 T cells during chronic viral infectionK99AI153537 · NIAID · VERSITI WISCONSIN, INC. · PI ZANDER, RYAN · 2020 to 2021
$224kReprogramming tumor-reactive CD8 T cells by targeting the IL-21-BATF pathway to treat melanomaF30CA246920 · NCI · VERSITI WISCONSIN, INC. · PI TOPCHYAN, PAYTSAR · 2020 to 2023
$200kMechanistic study of TCR signaling strength in CD8 T cell differentiation during pathogenesis of T1DMF30DK127526 · NIDDK · MEDICAL COLLEGE OF WISCONSIN · PI KASMANI, MOUJTABA Y · 2020 to 2023
$198kBATF-IRF4 complex controls transcriptional regulation and effector function of autoreactive CD8 T cells in type 1 diabetesF30DK108557 · NIDDK · VERSITI WISCONSIN, INC. · PI SCHAUDER, DAVID · 2016 to 2019
$191kNCI NIH HHS F30 CA246920NIAID NIH HHS K99 AI153537NIAID NIH HHS R00 AI153537NIAID NIH HHS R01 AI125741NIAID NIH HHS R01 AI148403NIDDK NIH HHS F30 DK108557NIDDK NIH HHS F30 DK127526NIGMS NIH HHS T32 GM080202
Abstract
During chronic viral infection, CD8
Indexed as
AnimalsAntigens, LyBasic-Leucine Zipper Transcription FactorsCD8-Positive T-LymphocytesCell DifferentiationCell LineCX3C Chemokine Receptor 1FemaleHepatocyte Nuclear Factor 1-alphaKruppel-Like Transcription FactorsLymphocytic ChoriomeningitisLymphocytic choriomeningitis virusMaleMiceMice, Inbred C57BLMice, KnockoutAntigens, LyBasic-Leucine Zipper Transcription FactorsBatf protein, mouseCX3C Chemokine Receptor 1Cx3cr1 protein, mouseHepatocyte Nuclear Factor 1-alphaHnf1a protein, mouseKlf2 protein, mouseKruppel-Like Transcription FactorsSignaling Lymphocytic Activation Molecule FamilySlamf6 protein, mouseT-bet Transcription FactorT-Box Domain Proteins
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.