Evidence map›Paper›PMID 34282212›Full record

ArticleScientific reports2021

Dynamics of inhaled corticosteroid use are associated with asthma attacks.

Joy Lee, Jacqueline Huvanandana, Juliet M Foster, Helen K Reddel, Michael J Abramson, Cindy Thamrin, Mark Hew

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Joy LeeAllergy, Asthma and Clinical Immunology, The Alfred Hospital, Alfred Health, 55 Commercial Road, Prahran, Melbourne, VIC, 3183, Australia. joy.lee@alfred.org.au.
Jacqueline HuvanandanaThe Woolcock Institute of Medical Research and The University of Sydney, 431 Glebe Point Road, Sydney, NSW, Australia.
Juliet M FosterThe Woolcock Institute of Medical Research and The University of Sydney, 431 Glebe Point Road, Sydney, NSW, Australia.
Helen K ReddelThe Woolcock Institute of Medical Research and The University of Sydney, 431 Glebe Point Road, Sydney, NSW, Australia.
Michael J AbramsonAllergy, Asthma and Clinical Immunology, The Alfred Hospital, Alfred Health, 55 Commercial Road, Prahran, Melbourne, VIC, 3183, Australia.
Cindy Thamrin *The Woolcock Institute of Medical Research and The University of Sydney, 431 Glebe Point Road, Sydney, NSW, Australia.
Mark Hew *Allergy, Asthma and Clinical Immunology, The Alfred Hospital, Alfred Health, 55 Commercial Road, Prahran, Melbourne, VIC, 3183, Australia.
Woolcock Institute of Medical Research · AUAlfred Health · AUThe Alfred Hospital · AUUniversity of Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inhaled corticosteroids (ICS) suppress eosinophilic airway inflammation in asthma, but patients may not adhere to prescribed use. Mean adherence-averaging total doses taken over prescribed-fails to capture many aspects of adherence. Patients with difficult-to-treat asthma underwent electronic monitoring of ICS, with data collected over 50 days. These were used to calculate entropy (H) a measure of irregular inhaler use over this period, defined in terms of transitional probabilities between different levels of adherence, further partitioned into increasing (H

Indexed as

Drug MonitoringAdministration, InhalationAdrenal Cortex HormonesAdultAgedAnti-Asthmatic AgentsAsthmaAustraliaDisease ProgressionFemaleHumansMaleMiddle AgedTreatment OutcomeYoung AdultAdrenal Cortex HormonesAnti-Asthmatic Agents

Identifiers

PMID34282212
PMCPMC8289909
OpenAlexW3186313862

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.