Evidence map›Paper›PMID 34282145›Full record

ArticleTranslational psychiatry2021

Compassion toward others and self-compassion predict mental and physical well-being: a 5-year longitudinal study of 1090 community-dwelling adults across the lifespan.

Ellen E Lee, Tushara Govind, Marina Ramsey, Tsung Chin Wu, Rebecca Daly, Jinyuan Liu, Xin M Tu, Martin P Paulus, Michael L Thomas, Dilip V Jeste

Open access · goldAbstract read
In one paragraph

Article in Translational psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
14.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 108 citations in OpenAlex.

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  3. Developing kind emotions in caring environments.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Ellen E LeeDepartment of Psychiatry, University of California San Diego, La Jolla, CA, USA. eel013@health.ucsd.edu.ORCID http://orcid.org/0000-0002-2250-765X
Tushara GovindSam and Rose Stein Institute for Research on Aging, University of California San Diego, La Jolla, CA, USA.
Marina RamseyDepartment of Psychiatry, University of California San Diego, La Jolla, CA, USA.ORCID http://orcid.org/0000-0002-5870-812X
Tsung Chin WuDepartment of Family Medicine and Public Health, University of California San Diego, La Jolla, CA, USA.
Rebecca DalyDepartment of Psychiatry, University of California San Diego, La Jolla, CA, USA.
Jinyuan LiuDepartment of Family Medicine and Public Health, University of California San Diego, La Jolla, CA, USA.
Xin M TuDepartment of Family Medicine and Public Health, University of California San Diego, La Jolla, CA, USA.
Martin P PaulusLaureate Institute for Brain Research, Tulsa, OK, USA.ORCID http://orcid.org/0000-0002-0825-3606
Michael L ThomasDepartment of Psychology, Colorado State University, Fort Collins, CO, USA.
Dilip V JesteDepartment of Psychiatry, University of California San Diego, La Jolla, CA, USA.
University of California San Diego · USColorado State University · USLaureate Institute for Brain Research · USUC San Diego Health System · US

Funding

UC San Diego Clinical and Translational Research InstituteUL1TR001442 · NCATS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI FIRESTEIN, GARY S, HOGARTH, MICHAEL · 2015 to 2024
$88.3M
Accelerated Inflammaging in SchizophreniaR01MH094151 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI EYLER, LISA T · 2012 to 2021
$7.4M
Inflammatory Mechanisms Linking Sleep Disturbances and Cognitive Deficits in Schizophrenia in Later LifeK23MH119375 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI LEE, ELLEN EUN-OK · 2019 to 2023
$1.0M
NCATS NIH HHS UL1 TR001442NIMH NIH HHS K23 MH119375NIMH NIH HHS R01 MH094151U.S. Department of Health & Human Services | NIH | National Institute of Mental Health (NIMH) K23MH119375-01
6 · The paper itself

Abstract

There is growing interest in the role of compassion in promoting health and well-being, with cross-sectional data showing an inverse correlation with loneliness. This is the first longitudinal study examining both compassion toward others (CTO) and compassion toward self (CTS) as predictors of mental and physical health outcomes including loneliness, across adult lifespan. We followed 552 women and 538 men in San Diego County for up to 7.5 (mean 4.8 and SD 2.2) years, using validated rating scales for CTO, CTS, and loneliness. Linear mixed-effects models were employed to examine age- and sex-related trajectories of CTO and CTS over time. Linear regression models were used to evaluate baseline and longitudinal relationships of CTO and CTS with mental well-being, physical well-being, and loneliness. CTS and CTO were weakly intercorrelated. Women had higher baseline CTO than men. While CTO was stable over time and across the lifespan, CTS scores had an inverse U-shaped relationship with age, peaking around age 77. There were significant baseline × slope interactions of both CTO and CTS predicting improvements in physical well-being in adults <60 years old. Increases in CTO and CTS predicted improvements in mental well-being. Higher baseline CTO and CTS as well as increases in CTO and CTS scores predicted lower loneliness scores at follow-up. Thus, CTO and CTS were associated with better mental well-being and loneliness across the adult lifespan, and physical well-being in younger adults, and are promising targets for interventions to improve health outcomes.

Indexed as

Independent LivingLongevityAdultAgedCross-Sectional StudiesEmpathyFemaleHumansLongitudinal StudiesMaleMiddle Aged

Identifiers

PMID34282145
PMCPMC8287292
OpenAlexW3183759980

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.