Evidence map›Paper›PMID 34282019›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2021

Widespread remodeling of the m

Kalanghad Puthankalam Srinivas, Daniel P Depledge, Jonathan S Abebe, Stephen A Rice, Ian Mohr, Angus C Wilson

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. oHSV-1-modulated mVirology journal · 2026
    Article
  6. Article
  7. Article
  8. m6A epigenetic modification of viral RNA is critical for the transmission cycle of mosquito-borne flaviviruses.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  9. Article
  10. Extended poly(A) tails are a shared feature of herpesvirus mRNAs.bioRxiv : the preprint server for biology · 2025
    Article
  11. Article
  12. RNA modification is the mark and strategy for host-microbe interactions.Cellular and molecular life sciences : CMLS · 2025
    Review
  13. Article
  14. Article
  15. Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  16. Article
  17. The role of NJournal of virology · 2025
    Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kalanghad Puthankalam SrinivasDepartment of Microbiology, New York University Grossman School of Medicine, New York University, New York, NY 10016.ORCID 0000-0002-8328-5173
Daniel P DepledgeDepartment of Medicine, New York University Grossman School of Medicine, New York University, New York, NY 10016.ORCID 0000-0002-4292-0599
Jonathan S AbebeDepartment of Medicine, New York University Grossman School of Medicine, New York University, New York, NY 10016.
Stephen A RiceDepartment of Microbiology, University of Minnesota Medical School, University of Minnesota, Minneapolis, MN 55455.ORCID 0000-0001-7703-3634
Ian MohrDepartment of Microbiology, New York University Grossman School of Medicine, New York University, New York, NY 10016.
Angus C WilsonDepartment of Microbiology, New York University Grossman School of Medicine, New York University, New York, NY 10016; Angus.Wilson@nyulangone.org.ORCID 0000-0002-5016-4164

Funding

Vaccine FacilityP30CA016087 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI ANIRBAN MAITRA · 1985 to 2026
$83.1M
Control of Translation in Herpesvirus Infected Cells - Resubmission - 1R01GM056927 · NIGMS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Ian J Mohr · 1999 to 2026
$7.6M
Virus Host Interactions that Regulate Translation in Cells Infected with HSV-1R01AI073898 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI MOHR, IAN J · 2008 to 2020
$5.0M
EPITRANSCRIPTOMIC REGULATION OF CYTOMEGALOVIRUS INFECTIONR01AI152543 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI DEPLEDGE, DANIEL PEARCE, MOHR, IAN J · 2020 to 2025
$2.7M
Viral manipulation of neuronal microRNAs to maintain trophic support and HSV latencyR21AI147163 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI WILSON, ANGUS C · 2019 to 2020
$475k
Modeling herpes simplex virus latency in human neuronsR21AI130618 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI WILSON, ANGUS C · 2018 to 2019
$466k
Viral factors promoting the release of cell-free HSV-1R21AI151617 · NIAID · UNIVERSITY OF MINNESOTA · PI RICE, STEPHEN A · 2020 to 2021
$424k
Epigenomic profiling of neurotrophic herpesvirus chromatin by controlled antibody-targeted cleavage.R03AI151358 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI WILSON, ANGUS C · 2020 to 2021
$170k
NCI NIH HHS P30 CA016087NIAID NIH HHS R01 AI073898NIAID NIH HHS R01 AI152543NIAID NIH HHS R03 AI151358NIAID NIH HHS R21 AI130618NIAID NIH HHS R21 AI147163NIAID NIH HHS R21 AI151617NIGMS NIH HHS R01 GM056927
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsCell Cycle ProteinsCell LineChlorocebus aethiopsGene Expression Regulation, EnzymologicHerpesvirus 1, HumanHumansMethyltransferasesRNA InterferenceRNA, MessengerRNA Processing, Post-TranscriptionalRNA-SeqRNA Splicing FactorsVero CellsVirus Replication6-methyladenine mRNA methyltransferaseCell Cycle ProteinsMethyltransferasesMETTL14 protein, humanMETTL3 protein, humanRNA, MessengerRNA Splicing FactorsWTAP protein, humandirect RNA sequencingherpes simplex virusN6-methyladenosinenanoporeRNA modification

Identifiers

PMID34282019
PMCPMC8325250

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.