Evidence map›Paper›PMID 34282001›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2021

HECT E3 Ubiquitin Ligase Nedd4 Is Required for Antifungal Innate Immunity.

Patrick K Nuro-Gyina, Na Tang, Hui Guo, Chengkai Yan, Qiuming Zeng, Thomas J Waldschmidt, Jian Zhang

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Akt-2 Is a Potential Therapeutic Target for Disseminated Candidiasis.Journal of immunology (Baltimore, Md. : 1950) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Patrick K Nuro-GyinaBiomedical Science Graduate Program, Ohio State University, Columbus, OH; and.ORCID 0000-0002-2811-1533
Na TangDepartment of Pathology, University of Iowa, Iowa City, IA.
Hui GuoDepartment of Pathology, University of Iowa, Iowa City, IA.
Chengkai YanDepartment of Pathology, University of Iowa, Iowa City, IA.
Qiuming ZengDepartment of Pathology, University of Iowa, Iowa City, IA.
Thomas J WaldschmidtDepartment of Pathology, University of Iowa, Iowa City, IA.ORCID 0000-0001-6147-6991
Jian ZhangBiomedical Science Graduate Program, Ohio State University, Columbus, OH; and zhang@uiowa.edu.ORCID 0000-0002-9523-5296
University of Iowa · US

Funding

NEDD4 IN T HELPER CELL DEVELOPMENT AND AUTOIMMUNITYR01AI090901 · NIAID · UNIVERSITY OF IOWA · PI WALDSCHMIDT, THOMAS J · 2010 to 2020
$4.0M
Regulation of Innate Immune System Sensing of C. Albicans InfectionsR01AI123253 · NIAID · UNIVERSITY OF IOWA · PI WALDSCHMIDT, THOMAS J · 2016 to 2020
$2.1M
Role of Protein Ubiquitination in SepsisR01AI121196 · NIAID · UNIVERSITY OF IOWA · PI ZHANG, JIAN · 2016 to 2020
$1.7M
NIAID NIH HHS R01 AI090901NIAID NIH HHS R01 AI121196NIAID NIH HHS R01 AI123253
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Antifungal AgentsCandidiasisAnimalsCandida albicansImmunity, InnateMiceMice, KnockoutUbiquitin-Protein LigasesAntifungal AgentsUbiquitin-Protein Ligases

Identifiers

PMID34282001
PMCPMC8324540
OpenAlexW3195728871

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.