Evidence map›Paper›PMID 34281630›Full record

ArticleJournal of the American Association for Laboratory Animal Science : JAALAS2021

Transcutaneous Ultrasound Guided Intraovarian Injection in Rats (

Etiele M Gomes, Endreo A P Dos Santos, Leonel F L Neto, Danielle R Padilha, Gabrielle C S Campos, Roberto Thiesen, Ingrid R L Machado, Maria Ligia A Mestieri

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PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the American Association for Laboratory Animal Science : JAALAS, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Etiele M GomesDivision of Small Animal Clinics, Surgery and Imaging, Federal University of Pampa, Uruguaiana, Rio Grande do Sul, Brazil;, Email: etielemaldonado@gmail.com.
Endreo A P Dos SantosDivision of Small Animal Clinics, Surgery and Imaging, Federal University of Pampa, Uruguaiana, Rio Grande do Sul, Brazil.
Leonel F L NetoDivision of Small Animal Clinics, Surgery and Imaging, Federal University of Pampa, Uruguaiana, Rio Grande do Sul, Brazil.
Danielle R PadilhaDivision of Small Animal Clinics, Surgery and Imaging, Federal University of Pampa, Uruguaiana, Rio Grande do Sul, Brazil.
Gabrielle C S CamposDivision of Anesthesiology, Federal University of Pampa, Uruguaiana, Rio Grande do Sul, Brazil.
Roberto ThiesenDivision of Anesthesiology, Federal University of Pampa, Uruguaiana, Rio Grande do Sul, Brazil.
Ingrid R L MachadoDivision of Small Animal Clinics, Surgery and Imaging, Federal University of Pampa, Uruguaiana, Rio Grande do Sul, Brazil.
Maria Ligia A MestieriDivision of Small Animal Clinics, Surgery and Imaging, Federal University of Pampa, Uruguaiana, Rio Grande do Sul, Brazil.
Universidade Federal do Pampa · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The goal of this study was to develop a method for ultrasound-guided percutaneous intraovarian injection in Wistar rats. Intraovarian administration of chemicals or needle aspiration of the ovary has been undertaken in some species, including humans, equines, and bovines. In rodents, which are widely used in scientific research, a technique for intraovarian injection without surgical exposure of the organ has not been described. The current study standardized the procedure of ovarian percutaneous injection of 0.9% sodium chloride guided by ultrasound in rats. The ovaries were measured by ultrasound imaging before and immediately after injection and showed a significant increase in ovarian length but not width. No clinical abnormalities were detected within 15 d after injection. These findings indicate that the steps of ultrasound localization of the organ, digital restraint, and correct needle insertion achieved successful intraovarian administration of saline without invasive surgery. These results document the feasibility of ultrasound-guided intraovarian percutaneous injection in rats and may be useful for future research on female reproduction and chemical sterilization.

Indexed as

NeedlesOvaryAnimalsCattleFemaleHorsesRatsRats, WistarUltrasonographyUltrasonography, Interventional

Identifiers

PMID34281630
PMCPMC8603366
OpenAlexW3183272646

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.