Evidence map›Paper›PMID 34281619›Full record

ReviewJournal of medical case reports2021

Nonhepatic hyperammonemic encephalopathy complications following bariatric surgery: a case report and review of the literature.

Nuphar Vinegrad, Orna Staretz-Chacham, Leonid Barski, Carmi Bartal

Open access · goldAbstract readCase ReportsReview
In one paragraph

Review in Journal of medical case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Nuphar VinegradInternal Medicine, Soroka University Medical Center, Ben Gurion University, Rager Street 151, 8480101, Beer Sheva, Israel. Nupharv@gmail.com.
Orna Staretz-ChachamMetabolic Clinic, Soroka University Medical Center, Ben Gurion University, Rager Street 151, 8480101, Beer Sheva, Israel.
Leonid BarskiInternal Medicine, Soroka University Medical Center, Ben Gurion University, Rager Street 151, 8480101, Beer Sheva, Israel.
Carmi BartalInternal Medicine, Soroka University Medical Center, Ben Gurion University, Rager Street 151, 8480101, Beer Sheva, Israel.
Soroka Medical Center · ILBen-Gurion University of the Negev · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHyperammonemic encephalopathy, a rare but fatal condition, is increasingly being reported as a possible complication of bariatric surgery. Here, we present a case of hyperammonemic encephalopathy, focusing on the clinical presentation, diagnostic measures, and our treatment methods, which resulted in a rare favorable outcome, emphasizing the unique role of renal replacement treatment. We also provide a detailed discussion of the mechanism through which hyperammonemia occurs secondarily to bariatric surgery. CASE PRESENTATION: A 44-year-old Moroccan Jew woman with a history of obesity presented in the hospital with urea cycle disorder that manifested after bariatric surgery. A rapid diagnostic process, together with conservative treatment with lactulose, nutritional supplementation, dietary protein restriction, and ammonia scavengers did not result in adequate improvement. Therefore, hemofiltration was performed, which yielded a favorable outcome.

conclusionsThe case findings indicate an association between hyperammonemic encephalopathy and bariatric surgery, and support early treatment with ammonia scavengers, as currently accepted. Nevertheless, if rapid improvement is not seen, it is advisable to consider hemodialysis or hemofiltration as early invasive strategies.

Indexed as

Bariatric SurgeryHyperammonemiaUrea Cycle Disorders, InbornAdultAmmoniaFemaleHumansObesityAmmoniaBariatric surgeryEncephalopathyHyperammonemiaUrea cycle disorder

Identifiers

PMID34281619
PMCPMC8290566
OpenAlexW3185710795

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.