Evidence map›Paper›PMID 34281609›Full record

SynthesisCritical care (London, England)2021

Treatment of the lung injury of drowning: a systematic review.

Ogilvie Thom, Kym Roberts, Susan Devine, Peter A Leggat, Richard C Franklin

Abstract readSystematic Review
In one paragraph

Synthesis in Critical care (London, England), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

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  5. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ogilvie ThomCollege of Public Health, Medical and Veterinary Sciences, James Cook University, Townsville, QLD, Australia. Ogilvie.Thom@my.jcu.edu.au.ORCID 0000-0002-4005-6645
Kym RobertsCollege of Public Health, Medical and Veterinary Sciences, James Cook University, Townsville, QLD, Australia.
Susan DevineCollege of Public Health, Medical and Veterinary Sciences, James Cook University, Townsville, QLD, Australia.
Peter A LeggatCollege of Public Health, Medical and Veterinary Sciences, James Cook University, Townsville, QLD, Australia.
Richard C FranklinCollege of Public Health, Medical and Veterinary Sciences, James Cook University, Townsville, QLD, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDrowning is a cause of significant global mortality. The mechanism of injury involves inhalation of water, lung injury and hypoxia. This systematic review addressed the following question: In drowning patients with lung injury, what is the evidence from primary studies regarding treatment strategies and subsequent patient outcomes?

methodsThe search strategy utilised PRISMA guidelines. Databases searched were MEDLINE, EMBASE, CINAHL, Web of Science and SCOPUS. There were no restrictions on publication date or age of participants. Quality of evidence was evaluated using GRADE methodology.

resultsForty-one papers were included. The quality of evidence was very low. Seventeen papers addressed the lung injury of drowning in their research question and 24 had less specific research questions, however included relevant outcome data. There were 21 studies regarding extra-corporeal life support, 14 papers covering the theme of ventilation strategies, 14 addressed antibiotic use, seven papers addressed steroid use and five studies investigating diuretic use. There were no clinical trials. One retrospective comparison of therapeutic strategies was found. There was insufficient evidence to make recommendations as to best practice when supplemental oxygen alone is insufficient. Mechanical ventilation is associated with barotrauma in drowning patients, but the evidence predates the practice of lung protective ventilation. There was insufficient evidence to make recommendations regarding adjuvant therapies.

conclusionsTreating the lung injury of drowning has a limited evidentiary basis. There is an urgent need for comparative studies of therapeutic strategies in drowning.

Indexed as

Treatment OutcomeAnti-Bacterial AgentsBarotraumaDrowningExtracorporeal Membrane OxygenationHumansLung InjuryRespiration, ArtificialAnti-Bacterial AgentsDrowningLung injuryNon-invasive ventilationReviewVentilation

Identifiers

PMID34281609
PMCPMC8287554

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.