Evidence map›Paper›PMID 34281536›Full record

ArticleMicrobial cell factories2021

Cellulose induced protein 1 (Cip1) from Trichoderma reesei enhances the enzymatic hydrolysis of pretreated lignocellulose.

Hexue Jia, Wan Sun, Xuezhi Li, Jian Zhao

Open access · goldAbstract read
In one paragraph

Article in Microbial cell factories, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 32 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Hexue JiaState Key Laboratory of Microbial Technology, Shandong University, No. 72, Binhai Road, Qingdao, 266237, Shandong, China.
Wan SunNational Glycoengineering Research Center, Shandong University, No. 72, Binhai Road, Qingdao, 266237, Shandong, China.
Xuezhi LiState Key Laboratory of Microbial Technology, Shandong University, No. 72, Binhai Road, Qingdao, 266237, Shandong, China. lixz@sdu.edu.cn.
Jian ZhaoState Key Laboratory of Microbial Technology, Shandong University, No. 72, Binhai Road, Qingdao, 266237, Shandong, China. zhaojian@sdu.edu.cn.ORCID http://orcid.org/0000-0001-6307-3491
Shandong University · CN

Funding

Innovative Research Group Project of the National Natural Science Foundation of China No.31870562Key Technology Research and Development Program of Shandong 2019GSF107009Key Technology Research and Development Program of Shandong 2019JZZY020223Natural Science Foundation of Shandong Province ZR2018MC024Natural Science Foundation of Shandong Province ZR2019ZD19
6 · The paper itself

Abstract

backgroundTrichoderma reesei is currently the main strain for the commercial production of cellulase. Cellulose induced protein 1 (Cip1) is one of the most abundant proteins in extracellular proteins of T. reesei. Reported literatures about Cip1 mainly focused on the regulation of Cip1 and its possible enzyme activities, but the effect of Cip1 on the enzymatic hydrolysis of lignocellulose and possible mechanism have not still been reported.

resultsIn this study, Cip1 from T. reesei was cloned, expressed and purified, and its effects on enzymatic hydrolysis of several different pretreated lignocellulose were investigated. It was found that Cip1 could promote the enzymatic hydrolysis of pretreated lignocellulose, and the promoting effect was significantly better than that of bovine serum albumin (BSA). And especially for the lignocellulosic substrate with high lignin content such as liquid hot water pretreated corn stover and corncob residue, the promoting effect of Cip1 was even better than that of the commercial cellulase when adding equal amount protein. It was also showed that the metal ions Zn

conclusionThe Cip1 from T. reesei could significantly promote the enzymatic hydrolysis of pretreated lignocellulose, and the promotion of Cip1 was even higher than that of commercial cellulase in the enzymatic hydrolysis of the substrates with high lignin content. This study will help us to better optimize cellulase to improve its ability to degrade lignocellulose, thereby reducing the cost of enzymes required for enzymatic hydrolysis.

Indexed as

CellulaseCloning, MolecularFungal ProteinsHydrolysisHypocrealesLigninCellulaseFungal ProteinsLigninlignocelluloseCellulaseCellulose induced protein 1Crystal structureEnzymatic hydrolysisLignocellulose

Identifiers

PMID34281536
PMCPMC8287770
OpenAlexW3183569791

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.