Evidence map›Paper›PMID 34281502›Full record

ArticleBMC infectious diseases2021

Assessing the impact of HIV support groups on antiretroviral therapy adherence and viral suppression in the African cohort study.

Prudence Mbah, Michael Iroezindu, Allahna L Esber, Nicole Dear, Domonique Reed, Yakubu Adamu, Abdulwasiu Bolaji Tiamiyu, Samirah Sani Mohammed, Hannah Kibuuka, Jonah Maswai and 6 more

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Prudence MbahU.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA.
Michael IroezinduU.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA. miroezindu@wrp-n.org.
Allahna L EsberU.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA.
Nicole DearU.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA.
Domonique ReedU.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA.
Yakubu AdamuU.S. Army Medical Research Directorate - Africa, Abuja, Nigeria.
Abdulwasiu Bolaji TiamiyuU.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA.
Samirah Sani MohammedU.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA.
Hannah KibuukaMakerere University Walter Reed Project, Kampala, Uganda.
Jonah MaswaiU.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA.
John OwuothU.S. Army Medical Research Directorate - Africa, Kisumu, Kenya.
Emmanuel BahemanaU.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA.
Julie A AkeU.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA.
Christina S PolyakU.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA.
Trevor A CrowellU.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA.
AFRICOS Study Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSupport groups for people living with HIV (PLWH) may improve HIV care adherence and outcomes. We assessed the impact of support group attendance on antiretroviral therapy (ART) adherence and viral suppression in four African countries.

methodsThe ongoing African Cohort Study (AFRICOS) enrolls participants at 12 clinics in Kenya, Uganda, Tanzania, and Nigeria. Self-reported attendance of any support group meetings, self-reported ART adherence, and HIV RNA are assessed every 6 months. Logistic regression models with generalized estimating equations were used to estimate adjusted odds ratios (aORs) and 95% confidence intervals (95% CIs) for support group attendance and other factors potentially associated with ART adherence and viral suppression.

resultsFrom January 2013 to December 1, 2019, 1959 ART-experienced PLWH were enrolled and 320 (16.3%) reported any support group attendance prior to enrollment. Complete ART adherence, with no missed doses in the last 30 days, was reported by 87.8% while 92.4% had viral suppression <1000copies/mL across all available visits. There was no association between support group attendance and ART adherence in unadjusted (OR 1.01, 95% CI 0.99-1.03) or adjusted analyses (aOR 1.00, 95% CI 0.98-1.02). Compared to PLWH who did not report support group attendance, those who did had similar odds of viral suppression in unadjusted (OR 0.99, 95% CI 0.978-1.01) and adjusted analyses (aOR 0.99, 95% CI 0.97-1.01).

conclusionSupport group attendance was not associated with significantly improved ART adherence or viral suppression, although low support group uptake may have limited our ability to detect a statistically significant impact.

Indexed as

Antiretroviral Therapy, Highly ActiveMedication AdherenceSelf-Help GroupsAdultAfrica, EasternCohort StudiesFemaleHIV InfectionsHumansLogistic ModelsMaleMiddle AgedSelf ReportViral LoadAfricaART adherenceHIVSupport groupViral suppression

Identifiers

PMID34281502
PMCPMC8290579

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.