Evidence map›Paper›PMID 34281490›Full record

ArticlemAbs

Animal- versus

Andrew R M Bradbury, Stefan Dübel, Achim Knappik, Andreas Plückthun

Abstract readVideo-Audio Media
In one paragraph

Article in mAbs. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Construction of Synthetic Antibody Phage Display Libraries.Methods in molecular biology (Clifton, N.J.) · 2023
    Article
  5. Frontiers in microbiology · 2022
    Review
  6. Review
  7. Review
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Andrew R M BradburySpecifica Inc., Santa Fe, NM, USA.ORCID 0000-0002-5567-8172
Stefan DübelDepartment of Biotechnology, Technische Universität Braunschweig, Braunschweig, Germany.
Achim KnappikBio-Rad, Puchheim, Germany.
Andreas PlückthunDepartment of Biochemistry, University of Zürich, Zürich, Switzerland.ORCID 0000-0003-4191-5306

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent recommendations from the European Union Reference Laboratory regarding the generation of antibodies using animals have stimulated significant debate. Here, four of the scientists who served on the Scientific Advisory Committee provide clarification of their views regarding the use of animals and

Indexed as

Animal Use AlternativesAntibodiesEuropean UnionHumansAntibodiesAntibodyantibody discoveryantibody therapeuticsimmunizationphage display

Identifiers

PMID34281490
PMCPMC8293942

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.