Evidence map›Paper›PMID 34281437›Full record

ArticleOtolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery2022

Mechanics of Total Drum Replacement Tympanoplasty Studied With Wideband Acoustic Immittance.

Kristine Elisabeth Eberhard, Salwa Fatima Masud, Inge M Knudson, Keshinisuthan Kirubalingam, Hamza Khalid, Aaron K Remenschneider, Hideko Heidi Nakajima

Open access · greenAbstract read
In one paragraph

Article in Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. The Transmission of Sound to the Cochlea in Normal and Pathological Human Middle Ears.Journal of the Association for Research in Otolaryngology : JARO · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Kristine Elisabeth EberhardDepartment of Otolaryngology-Head and Neck Surgery, Harvard Medical School and Massachusetts Eye and Ear, Boston, Massachusetts, USA.
Salwa Fatima MasudDepartment of Otolaryngology-Head and Neck Surgery, Harvard Medical School and Massachusetts Eye and Ear, Boston, Massachusetts, USA.
Inge M KnudsonMassachusetts Eye and Ear, Boston, Massachusetts, USA.
Keshinisuthan KirubalingamMassachusetts Eye and Ear, Boston, Massachusetts, USA.
Hamza KhalidMassachusetts Eye and Ear, Boston, Massachusetts, USA.
Aaron K RemenschneiderMassachusetts Eye and Ear, Boston, Massachusetts, USA.
Hideko Heidi NakajimaDepartment of Otolaryngology-Head and Neck Surgery, Harvard Medical School and Massachusetts Eye and Ear, Boston, Massachusetts, USA.
Massachusetts Eye and Ear Infirmary · USCopenhagen University Hospital · DKHarvard University · US

Funding

Middle-ear Mechanics in Normal and Pathological EarsR01DC004798 · NIDCD · MASSACHUSETTS EYE AND EAR INFIRMARY · PI NAKAJIMA, HIDEKO HEIDI · 2001 to 2016
$4.9M
Mechanisms of Conductive Presbycusis in HumansK08DC018575 · NIDCD · MASSACHUSETTS EYE AND EAR INFIRMARY · PI REMENSCHNEIDER, AARON KYLE · 2020 to 2024
$950k
Development of computational models to diagnose mechanical lesions of the earF31DC016761 · NIDCD · HARVARD MEDICAL SCHOOL · PI MASUD, SALWA · 2017 to 2018
$69k
NIDCD NIH HHS F31 DC016761NIDCD NIH HHS K08 DC018575NIDCD NIH HHS R01 DC004798
6 · The paper itself

Abstract

objectivePoor hearing outcomes often persist following total drum replacement tympanoplasty. To understand the mechanics of the reconstructed eardrum, we measured wideband acoustic immittance and compared the mechanical characteristics of fascia-grafted ears with the normal tympanic membrane. STUDY

designProspective comparison study.

settingTertiary care center.

methodsPatients who underwent uncomplicated total drum replacement with temporalis fascia grafts were identified. Ears with healed grafts, an aerated middle ear, and no other conductive abnormalities were included. All patients underwent pre- and postoperative audiometry. Wideband acoustic immittance was measured with absorbance and impedance computed. Fascia-grafted ears were compared with normal unoperated ears.

resultsEleven fascia-grafted ears without complications were included. Postoperatively, the median air-bone gap was 15 dB (250-4000 Hz), with variation across frequency and between ears. Fifty-six control ears were included. Absorbance of fascia-grafted ears was significantly lower than that of normal ears at 1 to 4 kHz (

conclusionThe mechanics of fascia-grafted ears differ from the normal tympanic membrane by having lower absorbance at mid- to high frequencies and thus poor sound transmission. The lower resistance in fascia-grafted ears may be due to poor coupling of the graft to the malleus. To improve sound transmission, grafts for tympanic membrane reconstructions would benefit from refined mechanical properties.

Indexed as

Acoustic Impedance TestsTympanoplastyAcousticsEar, MiddleHumansProspective Studiesabsorbanceconductive hearing lossfascia graftreflectancetotal drum replacementtympanoplastywideband acoustic immittance

Identifiers

PMID34281437
PMCPMC8912255
OpenAlexW3185244650

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.