Evidence map›Paper›PMID 34281290›Full record

ArticleInternational journal of molecular sciences2021

Identification of 3,4-Dihydro-2

Endah Dwi Hartuti, Takaya Sakura, Mohammed S O Tagod, Eri Yoshida, Xinying Wang, Kota Mochizuki, Rajib Acharjee, Yuichi Matsuo, Fuyuki Tokumasu, Mihoko Mori and 7 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Genetic analysis of pyrimidine biosynthetic enzymes inbioRxiv : the preprint server for biology · 2025
    Article
  5. Review
  6. Siccanin Is a Dual-Target Inhibitor ofPharmaceuticals (Basel, Switzerland) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 5 institutions in 2 countries.

Endah Dwi HartutiProgram for Nurturing Global Leaders in Tropical and Emerging Communicable Disease, Graduate School of Biomedical Science, Nagasaki University, Nagasaki 852-8523, Japan.
Takaya SakuraDepartment of Molecular Infection Dynamics, Institute of Tropical Medicine (NEKKEN), Nagasaki University, Nagasaki 852-8523, Japan.ORCID 0000-0002-8320-8485
Mohammed S O TagodSchool of Tropical Medicine and Global Health, Nagasaki University, Nagasaki 852-8523, Japan.
Eri YoshidaDepartment of Molecular Infection Dynamics, Institute of Tropical Medicine (NEKKEN), Nagasaki University, Nagasaki 852-8523, Japan.
Xinying WangSchool of Tropical Medicine and Global Health, Nagasaki University, Nagasaki 852-8523, Japan.
Kota MochizukiDepartment of Immunogenetics, Institute of Tropical Medicine (NEKKEN), Nagasaki University, Nagasaki 852-8523, Japan.
Rajib AcharjeeProgram for Nurturing Global Leaders in Tropical and Emerging Communicable Disease, Graduate School of Biomedical Science, Nagasaki University, Nagasaki 852-8523, Japan.
Yuichi MatsuoSchool of Tropical Medicine and Global Health, Nagasaki University, Nagasaki 852-8523, Japan.
Fuyuki TokumasuDepartment of Cellular Architecture Studies, Institute of Tropical Medicine (NEKKEN), Nagasaki University, Nagasaki 852-8523, Japan.ORCID 0000-0003-2790-1071
Mihoko MoriBiological Resource Center, NITE, Kisarazu, Chiba 292-0818, Japan.
Danang WaluyoLaboratory for Biotechnology, Agency for the Assessment and Application of Technology, South Tangerang 15314, Indonesia.ORCID 0000-0003-1280-5984
Kazuro ShiomiGraduate School of Infection Control Sciences, Kitasato University, Tokyo 108-0072, Japan.ORCID 0000-0003-1264-5116
Tomoyoshi NozakiDepartment of Biomedical Chemistry, Graduate School of Medicine, The University of Tokyo, Tokyo 113-0033, Japan.ORCID 0000-0003-1354-5133
Shinjiro HamanoProgram for Nurturing Global Leaders in Tropical and Emerging Communicable Disease, Graduate School of Biomedical Science, Nagasaki University, Nagasaki 852-8523, Japan.
Tomoo ShibaDepartment of Applied Biology, Graduate School of Science Technology, Kyoto Institute of Technology, Matsugasaki, Sakyo-ku, Kyoto 606-8585, Japan.ORCID 0000-0001-9312-1298
Kiyoshi KitaSchool of Tropical Medicine and Global Health, Nagasaki University, Nagasaki 852-8523, Japan.
Daniel Ken InaokaDepartment of Molecular Infection Dynamics, Institute of Tropical Medicine (NEKKEN), Nagasaki University, Nagasaki 852-8523, Japan.ORCID 0000-0002-9791-927X
Nagasaki University · JPKitasato University · JPKyoto Institute of Technology · JPNational Institute of Technology and Evaluation · JPThe University of Tokyo · JP

Funding

Japan Agency for Medical Research and Development 10000284Japan Agency for Medical Research and Development 14425718Japanese Ministry of Education, Science, Culture, Sports and Technology 16811362Japanese Ministry of Education, Science, Culture, Sports and Technology 16K19114Japanese Ministry of Education, Science, Culture, Sports and Technology 19H03436Japanese Ministry of Health and Welfare 17929833Japanese Ministry of Health and Welfare 20314363Japan Society for the Promotion of Science 18073004Japan Society for the Promotion of Science 18GS0314
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsAntimalarialsCell LineDihydroorotate DehydrogenaseDrug Evaluation, PreclinicalEnzyme InhibitorsHumansIminesOxidoreductases Acting on CH-CH Group DonorsPlasmodium falciparumProtozoan ProteinsPyrimidinesRecombinant ProteinsStructure-Activity RelationshipTriazolesAntimalarialsDihydroorotate DehydrogenaseDSM265Enzyme InhibitorsIminesOxidoreductases Acting on CH-CH Group DonorsProtozoan ProteinsPyrimidinespyrimido(1,2-c)(1,3)benzothiazin-6-imineRecombinant ProteinsTriazolesantimalarial drugdihydroorotate dehydrogenaseinhibitor screeningPlasmodium falciparumubiquinone

Identifiers

PMID34281290
PMCPMC8268581
OpenAlexW3179133447

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.