Evidence map›Paper›PMID 34281244›Full record

ArticleInternational journal of molecular sciences2021

Optogenetic Manipulation of Olfactory Responses in Transgenic Zebrafish: A Neurobiological and Behavioral Study.

Yun-Mi Jeong, Tae-Ik Choi, Kyu-Seok Hwang, Jeong-Soo Lee, Robert Gerlai, Cheol-Hee Kim

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Yun-Mi JeongDepartment of Biology, Chungnam National University, Daejeon 34134, Korea.
Tae-Ik ChoiDepartment of Biology, Chungnam National University, Daejeon 34134, Korea.
Kyu-Seok HwangDepartment of Biology, Chungnam National University, Daejeon 34134, Korea.ORCID 0000-0003-4606-1354
Jeong-Soo LeeDisease Target Structure Research Center, Korean Research Institute of Biosciences and Biotechnology, Daejeon 34141, Korea.
Robert GerlaiDepartment of Psychology, University of Toronto Mississauga, Mississauga, ON L5L 1C6, Canada.
Cheol-Hee KimDepartment of Biology, Chungnam National University, Daejeon 34134, Korea.ORCID 0000-0002-3019-0699
Chungnam National University · KRKorea Research Institute of Bioscience and Biotechnology · KRUniversity of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Olfaction is an important neural system for survival and fundamental behaviors such as predator avoidance, food finding, memory formation, reproduction, and social communication. However, the neural circuits and pathways associated with the olfactory system in various behaviors are not fully understood. Recent advances in optogenetics, high-resolution in vivo imaging, and reconstructions of neuronal circuits have created new opportunities to understand such neural circuits. Here, we generated a transgenic zebrafish to manipulate olfactory signal optically, expressing the Channelrhodopsin (ChR2) under the control of the olfactory specific promoter,

Indexed as

AnimalsAnimals, Genetically ModifiedChannelrhodopsinsCuesLarvaLightNerve NetNeuronsOdorantsOlfactory PerceptionOptogeneticsPhotic StimulationPromoter Regions, GeneticSmellSwimmingZebrafishChannelrhodopsinsZebrafish Proteinschannelrhodopsinolfactionoptogeneticszebrafish

Identifiers

PMID34281244
PMCPMC8269104
OpenAlexW3182522007

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.