Evidence map›Paper›PMID 34281195›Full record

ReviewInternational journal of molecular sciences2021

Regulatory T Cells-Related Genes Are under DNA Methylation Influence.

Magdalena Piotrowska, Mateusz Gliwiński, Piotr Trzonkowski, Dorota Iwaszkiewicz-Grzes

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. Pooled it
  2. Trial
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  5. Review
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  9. Article
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  12. Review
  13. Improving regulatory T cell production through mechanosensing.Journal of biomedical materials research. Part A · 2024
    Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Review
  19. Review
  20. Combinatorial Power of cfDNA, CTCs and EVs in Oncology.Diagnostics (Basel, Switzerland) · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Magdalena PiotrowskaDepartment of Medical Immunology, Medical University of Gdansk, 80-210 Gdańsk, Poland.
Mateusz GliwińskiDepartment of Medical Immunology, Medical University of Gdansk, 80-210 Gdańsk, Poland.
Piotr TrzonkowskiDepartment of Medical Immunology, Medical University of Gdansk, 80-210 Gdańsk, Poland.
Dorota Iwaszkiewicz-GrzesDepartment of Medical Immunology, Medical University of Gdansk, 80-210 Gdańsk, Poland.ORCID 0000-0003-1177-1874
Gdańsk Medical University · PL

Funding

Medical University of Gdansk statutory grant no. 02-0049/07/272
6 · The paper itself

Abstract

Regulatory T cells (Tregs) exert a highly suppressive function in the immune system. Disturbances in their function predispose an individual to autoimmune dysregulation, with a predominance of the pro-inflammatory environment. Besides

Indexed as

DNA MethylationCTLA-4 AntigenEpigenesis, GeneticForkhead Transcription FactorsGene ExpressionGene Expression RegulationGlucocorticoid-Induced TNFR-Related ProteinHumansIkaros Transcription FactorInterleukin-2 Receptor alpha SubunitLymphocyte ActivationT-Lymphocytes, RegulatoryCTLA-4 AntigenForkhead Transcription FactorsGlucocorticoid-Induced TNFR-Related ProteinIkaros Transcription FactorInterleukin-2 Receptor alpha SubunitDNA methylationepigenetic modifiersgene expressionTconvTregs

Identifiers

PMID34281195
PMCPMC8267835
OpenAlexW3174781364

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.