Evidence map›Paper›PMID 34281172›Full record

ReviewInternational journal of molecular sciences2021

Function of Circular RNAs in Fish and Their Potential Application as Biomarkers.

Golam Rbbani, Artem Nedoluzhko, Jorge Galindo-Villegas, Jorge M O Fernandes

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Golam RbbaniGenomics Division, Faculty of Biosciences and Aquaculture, Nord University, 8049 Bodø, Norway.
Artem NedoluzhkoGenomics Division, Faculty of Biosciences and Aquaculture, Nord University, 8049 Bodø, Norway.ORCID 0000-0001-7040-0892
Jorge Galindo-VillegasGenomics Division, Faculty of Biosciences and Aquaculture, Nord University, 8049 Bodø, Norway.ORCID 0000-0002-4250-2477
Jorge M O FernandesGenomics Division, Faculty of Biosciences and Aquaculture, Nord University, 8049 Bodø, Norway.ORCID 0000-0002-2550-1640

Funding

European Research Council 683210Norges Forskningsråd 250548/F20
6 · The paper itself

Abstract

Circular RNAs (circRNAs) are an emerging class of regulatory RNAs with a covalently closed-loop structure formed during pre-mRNA splicing. Recent advances in high-throughput RNA sequencing and circRNA-specific computational tools have driven the development of novel approaches to their identification and functional characterization. CircRNAs are stable, developmentally regulated, and show tissue- and cell-type-specific expression across different taxonomic groups. They play a crucial role in regulating various biological processes at post-transcriptional and translational levels. However, the involvement of circRNAs in fish immunity has only recently been recognized. There is also broad evidence in mammals that the timely expression of circRNAs in muscle plays an essential role in growth regulation but our understanding of their expression and function in teleosts is still very limited. Here, we discuss the available knowledge about circRNAs and their role in growth and immunity in vertebrates from a comparative perspective, with emphasis on cultured teleost fish. We expect that the interest in teleost circRNAs will increase substantially soon, and we propose that they may be used as biomarkers for selective breeding of farmed fish, thus contributing to the sustainability of the aquaculture sector.

Indexed as

AnimalsAquacultureBiomarkersFishesHigh-Throughput Nucleotide SequencingImmunityRNARNA, CircularRNA SplicingBiomarkersRNARNA, CircularaquaculturebiomarkercircRNAgrowthimmunitymyogenesisselective breeding

Identifiers

PMID34281172
PMCPMC8268770

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.