Evidence map›Paper›PMID 34281107›Full record

SynthesisInternational journal of environmental research and public health2021

Relationship between Prenatal or Postnatal Exposure to Pesticides and Obesity: A Systematic Review.

Helena Pinos, Beatriz Carrillo, Ana Merchán, Judit Biosca-Brull, Cristian Pérez-Fernández, María Teresa Colomina, Fernando Sánchez-Santed, Fernando Martín-Sánchez, Paloma Collado, Jorge L Arias and 1 more

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 37 citations in OpenAlex.

  1. Pooled it
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  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Helena PinosDepartment of Psychobiology, Faculty of Psychology, National Distance Education University (UNED), 28040 Madrid, Spain.ORCID 0000-0002-5323-6602
Beatriz CarrilloDepartment of Psychobiology, Faculty of Psychology, National Distance Education University (UNED), 28040 Madrid, Spain.ORCID 0000-0002-7393-3675
Ana MerchánDepartment of Psychology and Health Research Center (CEINSA), Almeria University, 04120 Almeria, Spain.
Judit Biosca-BrullResearch in Neurobehavior and Health (NEUROLAB), Universitat Rovira i Virgili, 43007 Tarragona, Spain.ORCID 0000-0001-7386-8271
Cristian Pérez-FernándezDepartment of Psychology and Health Research Center (CEINSA), Almeria University, 04120 Almeria, Spain.
María Teresa ColominaResearch in Neurobehavior and Health (NEUROLAB), Universitat Rovira i Virgili, 43007 Tarragona, Spain.ORCID 0000-0002-5619-4874
Fernando Sánchez-SantedDepartment of Psychology and Health Research Center (CEINSA), Almeria University, 04120 Almeria, Spain.ORCID 0000-0003-2190-2006
Fernando Martín-SánchezJoint Research Institute-UNED-Instituto de Salud Carlos III (IMIENS), 28029 Madrid, Spain.
Paloma ColladoDepartment of Psychobiology, Faculty of Psychology, National Distance Education University (UNED), 28040 Madrid, Spain.ORCID 0000-0002-2925-6806
Jorge L AriasLaboratory of Neuroscience, Department of Psychology, Instituto de Neurociencias del Principado de Asturias (INEUROPA), University of Oviedo, 33003 Oviedo, Spain.ORCID 0000-0003-0983-8654
Nélida M ConejoLaboratory of Neuroscience, Department of Psychology, Instituto de Neurociencias del Principado de Asturias (INEUROPA), University of Oviedo, 33003 Oviedo, Spain.ORCID 0000-0003-4749-5453
Universidad Nacional de Educación a Distancia · ESUniversity of Almería · ESUniversidad de Oviedo · ESUniversitat Rovira i Virgili · ESInstituto de Salud Carlos III · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years, the worldwide prevalence of overweight and obesity among adults and children has dramatically increased. The conventional model regarding the onset of obesity is based on an imbalance between energy intake and expenditure. However, other possible environmental factors involved, such as the exposure to chemicals like pesticides, cannot be discarded. These compounds could act as endocrine-disrupting chemicals (EDC) that may interfere with hormone activity related to several mechanisms involved in body weight control. The main objective of this study was to systematically review the data provided in the scientific literature for a possible association between prenatal and postnatal exposure to pesticides and obesity in offspring. A total of 25 human and 9 animal studies were analyzed. The prenatal, perinatal, and postnatal exposure to organophosphate, organochlorine, pyrethroid, neonicotinoid, and carbamate, as well as a combined pesticide exposure was reviewed. This systematic review reveals that the effects of pesticide exposure on body weight are mostly inconclusive, finding conflicting results in both humans and experimental animals. The outcomes reviewed are dependent on many factors, including dosage and route of administration, species, sex, and treatment duration. More research is needed to effectively evaluate the impact of the combined effects of different pesticides on human health.

Indexed as

PesticidesPyrethrinsAdultChildEnvironmental ExposureFemaleHumansNeonicotinoidsObesityOrganophosphatesPregnancyNeonicotinoidsOrganophosphatesPesticidesPyrethrinscarbamateschlorpyrifosneonicotinoidsobesityorganochlorineorganophosphatepesticidespyrethroids

Identifiers

PMID34281107
PMCPMC8295932
OpenAlexW3178118970

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.