Evidence map›Paper›PMID 34280978›Full record

ArticleInternational journal of environmental research and public health2021

Hospital Admissions Due to Ischemic Heart Diseases and Prescriptions of Cardiovascular Diseases Medications in England and Wales in the Past Two Decades.

Sara Ibrahim Hemmo, Abdallah Y Naser, Hassan Alwafi, Munthir M Mansour, Abeer F R Alanazi, Zahraa Jalal, Zahra Khalil Alsairafi, Vibhu Paudyal, Esra'a Alomari, Hamzeh Al-Momani and 6 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 39 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Observational
  8. Observational
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 11 institutions in 5 countries.

Sara Ibrahim HemmoDepartment of Applied Pharmaceutical Sciences and Clinical Pharmacy, Faculty of Pharmacy, Isra University, Amman 11622, Jordan.
Abdallah Y NaserDepartment of Applied Pharmaceutical Sciences and Clinical Pharmacy, Faculty of Pharmacy, Isra University, Amman 11622, Jordan.ORCID 0000-0001-8440-7446
Hassan AlwafiFaculty of Medicine, Umm Alqura University, Mecca 21514, Saudi Arabia.
Munthir M MansourDepartment of Internal Medicine, University of Arkansas for Medical Center, Little Rock, AR 72205, USA.
Abeer F R AlanaziDepartment of Pharmaceutical and Biological Sciences, UCL School of Pharmacy, London WC1E 6BT, UK.
Zahraa JalalSchool of Pharmacy, Institute of Clinical Sciences, University of Birmingham, Birmingham B15 2TT, UK.ORCID 0000-0002-6126-3379
Zahra Khalil AlsairafiDepartment of Pharmacy Practice, Kuwait University, Kuwait 12037, Kuwait.ORCID 0000-0003-1934-3751
Vibhu PaudyalSchool of Pharmacy, Institute of Clinical Sciences, University of Birmingham, Birmingham B15 2TT, UK.ORCID 0000-0002-4173-6490
Esra'a AlomariDepartment of Applied Pharmaceutical Sciences and Clinical Pharmacy, Faculty of Pharmacy, Isra University, Amman 11622, Jordan.
Hamzeh Al-MomaniDepartment of Pediatric, School of Medicine, Hashemite University, Zarqa 13133, Jordan.
Emad M SalawatiFamily Medicine Department, Faculty of Medicine, King Abdulaziz University, Jeddah 22254, Saudi Arabia.ORCID 0000-0001-6602-3473
Mohammed SamannodiFaculty of Medicine, Umm Alqura University, Mecca 21514, Saudi Arabia.ORCID 0000-0002-7937-5387
Mohammad S DairiFaculty of Medicine, Umm Alqura University, Mecca 21514, Saudi Arabia.
Abdel Qader Al BawabFaculty of Pharmacy, Al-Zaytoonah University of Jordan, Amman 11733, Jordan.
Moaath K Mustafa AliGreenebaum Comprehensive Cancer Center, University of Maryland, Baltimore, MD 20742, USA.ORCID 0000-0003-3289-2333
Saqer AlkharabshehHeart and Vascular Institute, Cleveland Clinic, Cleveland, OH 44195, USA.
Isra University · JOUmm al-Qura University · SAUniversity of Birmingham · GBAl-Zaytoonah University of Jordan · JOCleveland Clinic · USHashemite University · JOKing Abdulaziz University · SAKuwait University · KWUniversity College London · GBUniversity of Arkansas for Medical Sciences · USUniversity of Maryland, Baltimore · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe aim of this study was to explore the trend of ischemic heart disease (IHD) admission and the prescriptions of IHD medications in England and Wales.

methodsA secular trends study was conducted during the period of 1999 to 2019. We extracted hospital admission data for patients from all age groups from the Hospital Episode Statistics database in England and the Patient Episode Database for Wales. Prescriptions of IHD medications were extracted from the Prescription Cost Analysis database from 2004 to 2019. The chi-squared test was used to assess the difference between the admission rates and the difference between IHD medication prescription rates. The trends in IHD-related hospital admission and IHD-related medication prescription were assessed using a Poisson model. The correlation between hospital admissions for IHD and its IHD medication-related prescriptions was assessed using the Pearson correlation coefficient.

resultsOur study detected a significant increase in the rate of cardiovascular disease (CVD) medication prescriptions in England and Wales, representing a rise in the CVD medications prescription rate of 41.8% (from 539,334.95 (95% CI = 539,286.30-539,383.59) in 2004 to 764,584.55 (95% CI = 764,545.55-764,623.56) in 2019 prescriptions per 100,000 persons), with a mean increase of 2.8% per year during the past 15 years. This increase was connected with a reduction in the IHD hospital admission rate by 15.4% (from 838.50 (95% CI = 836.05-840.94) in 2004 to 709.78 (95% CI = 707.65-711.92) in 2019 per 100,000 persons, trend test,

conclusionThe rate of hospitalisation due to IHD has decreased in England and Wales during the past two decades. Hospitalisation due to IHD was strongly and negatively correlated with the increase in the rates of dispensing of IHD-related medications. Other factors contributing to this decline could be the increase in controlling IHD risk factors during the past few years. Future studies exploring other risk factors that are associated with IHD hospitalisation are warranted.

Indexed as

Cardiovascular DiseasesMyocardial IschemiaEnglandHospitalizationHospitalsHumansPrescriptionsWalesadmission rateIHDIHD medicationIHD medication rateIHD ratetrend

Identifiers

PMID34280978
PMCPMC8297245
OpenAlexW3178204773

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.