Evidence map›Paper›PMID 34280454›Full record

ArticleBrazilian journal of anesthesiology (Elsevier)

Cannabis and pain: a scoping review.

Camila Pantoja-Ruiz, Paula Restrepo-Jimenez, Camilo Castañeda-Cardona, Alexandra Ferreirós, Diego Rosselli

Open access · diamondAbstract readScoping Review
In one paragraph

Article in Brazilian journal of anesthesiology (Elsevier). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
7.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 65 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. A Scoping Systematic Review of Cannabis Use in Endometriosis.The Australian & New Zealand journal of obstetrics & gynaecology · 2026
    Article
  5. Article
  6. The Use of Cannabis-Based Medicine in Selected Neurological Disorders.Current topics in behavioral neurosciences · 2026
    Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. Natural Products Derived from Cannabis sativa for Pain Management.Handbook of experimental pharmacology · 2025
    Review
  12. Review
  13. Article
  14. Article
  15. Transitional Pain Service: An Update.Current pain and headache reports · 2024
    Review
  16. Article
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Camila Pantoja-RuizPontificia Universidad Javeriana, Medical School, Hospital Universitario San Ignacio, Bogotá, Colombia.
Paula Restrepo-JimenezPontificia Universidad Javeriana, Medical School, Hospital Universitario San Ignacio, Bogotá, Colombia.
Camilo Castañeda-CardonaNeuroEconomix, Bogotá, Colombia.
Alexandra FerreirósHospital Universitario San Ignacio, Bogotá, Colombia.
Diego RosselliPontificia Universidad Javeriana, Medical School, Bogotá, Colombia. Electronic address: diego.rosselli@gmail.con.
Pontificia Universidad Javeriana · COHospital Universitario San Ignacio · COInstituto Neurológico de Colombia · CO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

For centuries, cannabis has been used with many different purposes, including medicinal use, usually bypassing any formal approval process. However, during the last decade, interest in cannabis in medicine has been increasing, and several countries, including the United States and Canada, have produced their own legislation about marihuana and cannabis-based medicines. Because of this, interest in research has been increasing and evidence about its medical effects is becoming necessary. We conducted a review examining the evidence of cannabis in pain. Cannabis had been shown to be useful in acute and chronic pain, however recently, these results have been controverted. Within the different types of chronic pain, it has a weak evidence for neuropathic, rheumatic pain, and headache, modest evidence for multiple sclerosis related pain, and as adjuvant therapy in cancer pain. There is no strong evidence to recommend cannabis in order to decrease opioids in patients with chronic use. Even though cannabis-based medications appear to be mostly safe, mild adverse effects are common; somnolence, sedation, amnesia, euphoric mood, hyperhidrosis, paranoia, and confusion may limit the use of cannabis in clinical practice. Risks have not been systematically analyzed. Special concern arises on how adverse effect might affect vulnerable population such as elderly patients. More research is needed in order to evaluate benefits and risks, as well as the ideal administration route and dosages. As cannabis use increases in several countries, answers to these questions might be coming soon.

Indexed as

CannabisChronic PainMedical MarijuanaNeuralgiaAgedAnalgesicsHumansAnalgesicsMedical MarijuanaAcute painCancer painCannabisChronic painNeuralgiaReview

Identifiers

PMID34280454
PMCPMC9373074
OpenAlexW3186913564

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.