Evidence map›Paper›PMID 34280204›Full record

ArticlePLoS neglected tropical diseases2021

The impact of dengue illness on social distancing and caregiving behavior.

Kathryn L Schaber, Amy C Morrison, William H Elson, Helvio Astete-Vega, Jhonny J Córdova-López, Esther Jennifer Ríos López, W Lorena Quiroz Flores, Alfonso S Vizcarra Santillan, Thomas W Scott, Lance A Waller and 7 more

Abstract read
In one paragraph

Article in PLoS neglected tropical diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Kathryn L SchaberProgram of Population Biology, Ecology and Evolution, Emory University, Atlanta, Georgia, United States of America.ORCID 0000-0002-6669-9534
Amy C MorrisonDepartment of Virology and Emerging Infections, U.S. Naval Medical Research Unit No. 6, Lima and Iquitos, Peru.
William H ElsonDepartment of Entomology and Nematology, University of California, Davis, California, United States of America.ORCID 0000-0002-8630-1378
Helvio Astete-VegaDepartment of Virology and Emerging Infections, U.S. Naval Medical Research Unit No. 6, Lima and Iquitos, Peru.ORCID 0000-0001-6984-7849
Jhonny J Córdova-LópezDepartment of Entomology and Nematology, University of California, Davis, California, United States of America.
Esther Jennifer Ríos LópezDepartment of Virology and Emerging Infections, U.S. Naval Medical Research Unit No. 6, Lima and Iquitos, Peru.
W Lorena Quiroz FloresDepartment of Virology and Emerging Infections, U.S. Naval Medical Research Unit No. 6, Lima and Iquitos, Peru.
Alfonso S Vizcarra SantillanDepartment of Entomology and Nematology, University of California, Davis, California, United States of America.
Thomas W ScottDepartment of Entomology and Nematology, University of California, Davis, California, United States of America.ORCID 0000-0003-2947-8123
Lance A WallerDepartment of Biostatistics and Bioinformatics, Rollins School of Public Health, Emory University, Atlanta, Georgia, United States of America.ORCID 0000-0001-5002-8886
Uriel KitronDepartment of Environmental Sciences, Emory University, Atlanta, Georgia, United States of America.ORCID 0000-0003-0493-2043
Christopher M BarkerDepartment of Pathology, Microbiology, and Immunology, School of Veterinary Medicine, University of California, Davis, California, United States of America.ORCID 0000-0002-7941-346X
T Alex PerkinsDepartment of Biological Sciences and Eck Institute for Global Health, University of Notre Dame, Notre Dame, Indiana, United States of America.
Alan L RothmanInstitute for Immunology and Informatics and Department of Cell and Molecular Biology, University of Rhode Island, Providence, Rhode Island, United States of America.
Gonzalo M Vazquez-ProkopecProgram of Population Biology, Ecology and Evolution, Emory University, Atlanta, Georgia, United States of America.ORCID 0000-0002-0710-270X
John P ElderSchool of Public Health, San Diego State University, San Diego, California, United States of America.
Valerie A Paz-SoldanDepartment of Global Community Health and Behavioral Sciences, Tulane School of Public Health and Tropical Medicine, New Orleans, Louisiana, United States of America.

Funding

Surveillance Core (B)P01AI098670 · NIAID · UNIVERSITY OF CALIFORNIA AT DAVIS · PI SCOTT, THOMAS WALLACE · 2014 to 2018
$7.9M
NIAID NIH HHS P01 AI098670
6 · The paper itself

Abstract

backgroundHuman mobility among residential locations can drive dengue virus (DENV) transmission dynamics. Recently, it was shown that individuals with symptomatic DENV infection exhibit significant changes in their mobility patterns, spending more time at home during illness. This change in mobility is predicted to increase the risk of acquiring infection for those living with or visiting the ill individual. It has yet to be considered, however, whether social contacts are also changing their mobility, either by socially distancing themselves from the infectious individual or increasing contact to help care for them. Social, or physical, distancing and caregiving could have diverse yet important impacts on DENV transmission dynamics; therefore, it is necessary to better understand the nature and frequency of these behaviors including their effect on mobility. METHODOLOGY AND PRINCIPAL

findingsThrough community-based febrile illness surveillance and RT-PCR infection confirmation, 67 DENV positive (DENV+) residents were identified in the city of Iquitos, Peru. Using retrospective interviews, data were collected on visitors and home-based care received during the illness. While 15% of participants lost visitors during their illness, 22% gained visitors; overall, 32% of all individuals (particularly females) received visitors while symptomatic. Caregiving was common (90%), particularly caring by housemates (91%) and caring for children (98%). Twenty-eight percent of caregivers changed their behavior enough to have their work (and, likely, mobility patterns) affected. This was significantly more likely when caring for individuals with low "health-related quality of well-being" during illness (Fisher's Exact, p = 0.01). CONCLUSIONS/SIGNIFICANCE: Our study demonstrates that social contacts of individuals with dengue modify their patterns of visitation and caregiving. The observed mobility changes could impact a susceptible individual's exposure to virus or a presymptomatic/clinically inapparent individual's contribution to onward transmission. Accounting for changes in social contact mobility is imperative in order to get a more accurate understanding of DENV transmission.

Indexed as

Physical DistancingAdolescentAdultCaregiversChildData CollectionDengueFemaleHumansMalePeruYoung Adult

Identifiers

PMID34280204
PMCPMC8354465

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.