Evidence map›Paper›PMID 34280144›Full record

ArticleThe American journal of tropical medicine and hygiene2021

Nosocomial Respiratory Infections in a Rural Zambian Hospital.

Gideon Loevinsohn, Justin Hardick, Thomas Mehoke, Pamela Sinywimaanzi, Mutinta Hamahuwa, Katherine Z J Fenstermacher, Kathryn Shaw-Saliba, Peter Thielen, Jared Evans, Kenneth Bowden and 8 more

Open access · greenAbstract read
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 6 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 6 institutions in 2 countries.

Gideon Loevinsohn1Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland.
Justin Hardick3Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Thomas Mehoke4Applied Physics Laboratory, Johns Hopkins University, Laurel, Maryland.
Pamela Sinywimaanzi5Macha Research Trust, Choma, Zambia.
Mutinta Hamahuwa5Macha Research Trust, Choma, Zambia.
Katherine Z J Fenstermacher6Department of Emergency Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Kathryn Shaw-Saliba6Department of Emergency Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Peter Thielen4Applied Physics Laboratory, Johns Hopkins University, Laurel, Maryland.
Jared Evans4Applied Physics Laboratory, Johns Hopkins University, Laurel, Maryland.
Kenneth Bowden4Applied Physics Laboratory, Johns Hopkins University, Laurel, Maryland.
Kristina Zudock4Applied Physics Laboratory, Johns Hopkins University, Laurel, Maryland.
Lauren M Sauer6Department of Emergency Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Mwaka Monze7Virology Laboratory, University Teaching Hospital, Lusaka, Zambia.
Charlotte A Gaydos3Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Richard E Rothman6Department of Emergency Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Andrew Pekosz8Department of Molecular Microbiology and Immunology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland.
Philip E Thuma5Macha Research Trust, Choma, Zambia.
Catherine G Sutcliffe1Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland.
Johns Hopkins University · USJohns Hopkins University Applied Physics Laboratory · USGolden Valley Agricultural Research Trust · ZMJohns Hopkins Medicine · USUniversity of Baltimore · USUniversity Teaching Hospital · ZM

Funding

Medical Scientist Training ProgramT32GM136577 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI ANDREA L COX · 2020 to 2026
$13.4M
NIGMS NIH HHS T32 GM136577
6 · The paper itself

Abstract

The burden of nosocomial respiratory infections in rural southern Africa is poorly understood. We established a surveillance program at a rural Zambian hospital to detect influenza-like illness (ILI) and respiratory infections among hospitalized patients and a cohort of healthcare workers (HCWs). Nasopharyngeal specimens from symptomatic patients and HCWs underwent broadly multiplexed molecular testing to detect viruses and atypical bacteria. During 1 year of surveillance, 15 patients (1.7% of admissions) developed ILI more than 48 hours after admission. Among 44 HCWs, 19 (43%) experienced at least one ILI episode, with a total of 31 ILI episodes detected. Respiratory viruses were detected in 45% of patient and 55% of HCW specimens. The cumulative incidence of influenza infection among HCWs over 1 year was 9%. Overall, respiratory viruses were commonly found among patients and HCWs in a rural Zambian hospital with limited infection control infrastructure.

Indexed as

Hospitals, RuralAdultChildChild, PreschoolCohort StudiesCross InfectionFemaleHealth PersonnelHumansInfection ControlInfectious Disease Transmission, Professional-to-PatientInfluenza, HumanInfluenza VaccinesMalePatients' RoomsPicornaviridae InfectionsInfluenza Vaccines

Identifiers

PMID34280144
PMCPMC8592331
OpenAlexW3183897146

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.