Evidence map›Paper›PMID 34280034›Full record

ArticleThe CRISPR journal2021

Evaluation of Gene Knockouts by CRISPR as Potential Targets for the Genetic Engineering of the Mosquito

Xuechun Feng, Lukas Kambic, Jared H K Nishimoto, Floyd A Reed, Jai A Denton, Jolene T Sutton, Valentino M Gantz

Open access · greenAbstract read
In one paragraph

Article in The CRISPR journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Xuechun FengSection of Cell and Developmental Biology, University of California San Diego, La Jolla, California, USA; University of Monash, Clayton, Australia.
Lukas KambicDepartment of Biology, University of Hawai'i at Hilo, Hilo, Hawai'i, USA; University of Monash, Clayton, Australia.
Jared H K NishimotoDepartment of Biology, University of Hawai'i at Hilo, Hilo, Hawai'i, USA; University of Monash, Clayton, Australia.
Floyd A ReedSchool of Life Sciences, University of Hawai'i at Mānoa, Honolulu, Hawai'i, USA; and University of Monash, Clayton, Australia.
Jai A DentonInstitute of Vector-borne Disease, University of Monash, Clayton, Australia.
Jolene T SuttonDepartment of Biology, University of Hawai'i at Hilo, Hilo, Hawai'i, USA; University of Monash, Clayton, Australia.
Valentino M GantzSection of Cell and Developmental Biology, University of California San Diego, La Jolla, California, USA; University of Monash, Clayton, Australia.
University of Hawaii at Hilo · USMonash University · AUUniversity of Hawaiʻi at Mānoa · USVector & Vector-Borne Diseases Research Institute · TZ

Funding

The Control of Insect Metabolism through Nutrition-based SymbiosisP20GM125508 · NIGMS · UNIVERSITY OF HAWAII AT MANOA · PI Garrett W. Roell · 2018 to 2026
$21.2M
Development, characterization and application of CRISPR/Cas9 gene drive technologies and related active genetic elements to benefit research and society at largeDP5OD023098 · OD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GANTZ, VALENTINO MATTEO · 2016 to 2020
$1.9M
NIGMS NIH HHS P20 GM125508NIH HHS DP5 OD023098
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Clustered Regularly Interspaced Short Palindromic RepeatsCRISPR-Cas SystemsGene EditingGene Knockout TechniquesGenetic EngineeringAnimalsCulexCulicidaeGene TargetingGenetic LociMicroinjectionsMutationPhenotypeRNA, Guide, CRISPR-Cas SystemsRNA, Guide, CRISPR-Cas Systems

Identifiers

PMID34280034
PMCPMC8392076
OpenAlexW3184630515

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.