Evidence map›Paper›PMID 34280002›Full record

ArticleJournal of bacteriology2021

Bacterial Cytological Profiling Identifies Rhodanine-Containing PAINS Analogs as Specific Inhibitors of

Elizabeth T Montaño, Jason F Nideffer, Joseph Sugie, Eray Enustun, Adam B Shapiro, Hannah Tsunemoto, Alan I Derman, Kit Pogliano, Joe Pogliano

Open access · greenAbstract read
In one paragraph

Article in Journal of bacteriology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Sensing of Antibiotic-Bacteria Interactions.Antibiotics (Basel, Switzerland) · 2023
    Review
  6. Article
  7. Article
  8. Seeing the bigger picture.Nature reviews. Microbiology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Elizabeth T Montaño *Division of Biological Sciences, University of California-San Diego, La Jolla, California, USA.
Jason F Nideffer *Division of Biological Sciences, University of California-San Diego, La Jolla, California, USA.
Joseph SugieDivision of Biological Sciences, University of California-San Diego, La Jolla, California, USA.
Eray EnustunDivision of Biological Sciences, University of California-San Diego, La Jolla, California, USA.
Adam B ShapiroEntasis Therapeutics, Gatehouse Park BioHub, Waltham, Massachusetts, USA.ORCID 0000-0002-2662-6146
Hannah TsunemotoDivision of Biological Sciences, University of California-San Diego, La Jolla, California, USA.
Alan I DermanDivision of Biological Sciences, University of California-San Diego, La Jolla, California, USA.
Kit PoglianoDivision of Biological Sciences, University of California-San Diego, La Jolla, California, USA.
Joe PoglianoDivision of Biological Sciences, University of California-San Diego, La Jolla, California, USA.
University of California San Diego · USEntasis Therapeutics (United States) · US

Funding

UCSD/SDSU IRACDAK12GM068524 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI TREJO, JOANN · 2003 to 2025
$24.4M
Targeted discovery of antibiotics from cave bacteriaR01AI117712 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MOORE, BRADLEY S, POGLIANO, JOSEPH A · 2016 to 2019
$2.8M
NIAID NIH HHS R01 AI117712NIGMS NIH HHS K12 GM068524NIH HHS RO1AI117712
6 · The paper itself

Abstract

In this study, we sought to determine whether an

Indexed as

Anti-Bacterial AgentsDNA, BacterialDrug DiscoveryEscherichia coliGene Expression Regulation, BacterialGene Expression Regulation, EnzymologicGenome, BacterialMicrobial Sensitivity TestsMicrobial ViabilityModels, MolecularMolecular StructureNucleoside-Phosphate KinaseProtein ConformationRhodanineAnti-Bacterial AgentsDNA, BacterialdTMP kinaseNucleoside-Phosphate KinaseRhodanineantibioticbacterial cytological profilingE. colimechanismPAINSSAR

Identifiers

PMID34280002
PMCPMC8425406
OpenAlexW3183274693

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.