Evidence map›Paper›PMID 34279932›Full record

ArticleThe Journal of organic chemistry2021

Self-Assembly of Functionalized Lipophilic Guanosines into Cation-Free Stacked Guanine-Quartets.

Marilena Campitiello, Alessio Cremonini, Marco A Squillaci, Silvia Pieraccini, Artur Ciesielski, Paolo Samorì, Stefano Masiero

Abstract read
In one paragraph

Article in The Journal of organic chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Guanine Crystallization by Particle Attachment.Journal of the American Chemical Society · 2025
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Marilena CampitielloDipartimento di Chimica "Giacomo Ciamician", Alma Mater Studiorum-Università di Bologna, Via S. Giacomo 11, Bologna 40126, Italy.
Alessio CremoniniDipartimento di Chimica "Giacomo Ciamician", Alma Mater Studiorum-Università di Bologna, Via S. Giacomo 11, Bologna 40126, Italy.
Marco A SquillaciUniversité de Strasbourg and CNRS, ISIS, 8 allée Gaspard Monge, Strasbourg 67000, France.
Silvia PieracciniDipartimento di Chimica "Giacomo Ciamician", Alma Mater Studiorum-Università di Bologna, Via S. Giacomo 11, Bologna 40126, Italy.
Artur CiesielskiUniversité de Strasbourg and CNRS, ISIS, 8 allée Gaspard Monge, Strasbourg 67000, France.ORCID 0000-0003-3542-4092
Paolo SamorìUniversité de Strasbourg and CNRS, ISIS, 8 allée Gaspard Monge, Strasbourg 67000, France.ORCID 0000-0001-6256-8281
Stefano MasieroDipartimento di Chimica "Giacomo Ciamician", Alma Mater Studiorum-Università di Bologna, Via S. Giacomo 11, Bologna 40126, Italy.ORCID 0000-0001-6197-8297

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The hierarchical self-assembly of various lipophilic guanosines exposing either a phenyl or a ferrocenyl group in the C(8) position was investigated. In a solution, all the derivatives were found to self-assemble primarily into isolated guanine (G)-quartets. In spite of the apparent similar bulkiness of the two substituents, most of the derivatives form disordered structures in the solid state, whereas a specific 8-phenyl derivative self-assembles into an unprecedented, cation-free stacked G-quartet architecture.

Indexed as

G-QuadruplexesCationsGuanineGuanosineCationsGuanineGuanosine

Identifiers

PMID34279932
PMCPMC8389894

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.