Evidence map›Paper›PMID 34279713›Full record

SynthesisLangenbeck's archives of surgery2022

Simultaneous pancreas and kidney transplantation for end-stage kidney disease patients with type 2 diabetes mellitus: a systematic review and meta-analysis.

Yu Cao, Xiaoli Liu, Xiangyu Lan, Kaiwen Ni, Lin Li, Yingxin Fu

Open access · hybridAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Langenbeck's archives of surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Reassessing Simultaneous Pancreas-Kidney Vs. Kidney Transplant Alone: A Propensity-Weighted Analysis of Survival and Morbidity.Transplant international : official journal of the European Society for Organ Transplantation · 2025
    Article
  3. Simultaneous Pancreas-Kidney Versus Kidney Transplant Alone: Real-World Outcomes in a Propensity-Matched Global Cohort.Transplant international : official journal of the European Society for Organ Transplantation · 2025
    Article
  4. Analysis of Rejection, Infection and Surgical Outcomes in Type I Versus Type II Diabetic Recipients After Simultaneous Pancreas-Kidney Transplantation.Transplant international : official journal of the European Society for Organ Transplantation · 2024
    Article
  5. Simultaneous pancreas-kidney transplantation: Early complications and long-term outcomes - a single-center experience.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Yu CaoDepartment of Kidney and Pancreas Transplantation, Tianjin First Central Hospital, Tianjin, China.
Xiaoli LiuResearch Center of Clinical Epidemiology, Peking University Third Hospital, Beijing, China.
Xiangyu LanDepartment of Kidney and Pancreas Transplantation, Tianjin First Central Hospital, Tianjin, China.
Kaiwen NiResearch Center of Clinical Epidemiology, Peking University Third Hospital, Beijing, China.
Lin LiDepartment of Kidney and Pancreas Transplantation, Tianjin First Central Hospital, Tianjin, China.
Yingxin FuDepartment of Kidney and Pancreas Transplantation, Tianjin First Central Hospital, Tianjin, China. yingxinfu@nankai.edu.cn.ORCID http://orcid.org/0000-0001-8010-224X
Tianjin First Center Hospital · CNPeking University · CN

Funding

Major Research Plan NO.8197033298Tianjin Municipal Health Bureau NO.RC20090Tianjin Municipal Health Bureau NO.ZC20167
6 · The paper itself

Abstract

purposeThe indications for patients with type 2 diabetes mellitus (T2DM) combined with end-stage kidney disease (ESKD) undertaking simultaneous pancreas and kidney transplantation (SPK) remain an unresolved issue. This study aimed to systematically review the survival outcomes of SPK among T2DM-ESKD patients.

methodsOnline databases including PubMed, MEDLINE, EMBASE, and the CENTRAL Library, CNKI, Chinese Biomedical Literature Database, and Wan-Fang database were used to locate the studies of ESKD patients with T2DM undertaking SPK up to May 2021. A third reviewer was consulted if there were disagreements. Data were analyzed with STATA (15.0).

resultsNine cohort studies were identified. The pooled 1-year, 3-year, and 5-year patient survival rates of patients with T2DM and ESKD after SPK were 98%, 95%, and 91% respectively. Comparing the treatment effect of SPK between type 1 diabetes mellitus (T1DM) and T2DM, the survival estimates were comparable. For T2DM patients, SPK had a survival advantage compared with KTA.

conclusionsThe synthesized clinical outcomes of T2DM patients with ESKD after SPK were relatively better than KTA, but a subset of T2DM-ESKD patients who would benefit the most from SPK was to be defined. PROSPERO registration number CRD42019118321. Date of registration: 14 Jan 2019 (retrospectively registered).

Indexed as

Diabetes Mellitus, Type 2Kidney Failure, ChronicKidney TransplantationPancreas TransplantationGraft SurvivalHumansPancreasKidney transplantation aloneMeta-analysisSimultaneous pancreas and kidney transplantationSurvival outcomesType II diabetes

Identifiers

PMID34279713
PMCPMC9151548
OpenAlexW3184079411

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.