Evidence map›Paper›PMID 34279699›Full record

ArticleCellular and molecular life sciences : CMLS2021

SLC4A2 anion exchanger promotes tumour cell malignancy via enhancing net acid efflux across golgi membranes.

Elham Khosrowabadi, Antti Rivinoja, Maija Risteli, Anne Tuomisto, Tuula Salo, Markus J Mäkinen, Sakari Kellokumpu

Open access · hybridAbstract read
In one paragraph

Article in Cellular and molecular life sciences : CMLS, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Molecular Characterization of Anion Exchanger 2 inInternational journal of molecular sciences · 2025
    Article
  3. Article
  4. Review
  5. Acid-base transporters in the context of tumor heterogeneity.Pflugers Archiv : European journal of physiology · 2024
    Review
  6. Review
  7. Article
  8. Review
  9. The Golgi as a "Proton Sink" in Cancer.Frontiers in cell and developmental biology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Elham KhosrowabadiFaculty of Biochemistry and Molecular Medicine, University of Oulu (Oulun Yliopisto), Aapistie 7A, PO BOX 5400, 90014, Oulu, Finland. elham.khosrowabadi@oulu.fi.
Antti RivinojaNorthern Finland Laboratory Centre, Oulu, Finland.
Maija RisteliCancer and Translational Medicine Research Unit, University of Oulu, Oulu, Finland.
Anne TuomistoMedical Research Centre, Oulu University Hospital, Oulu, Finland.
Tuula SaloCancer and Translational Medicine Research Unit, University of Oulu, Oulu, Finland.
Markus J MäkinenMedical Research Centre, Oulu University Hospital, Oulu, Finland.
Sakari KellokumpuFaculty of Biochemistry and Molecular Medicine, University of Oulu (Oulun Yliopisto), Aapistie 7A, PO BOX 5400, 90014, Oulu, Finland. sakari.kellokumpu@oulu.fi.ORCID http://orcid.org/0000-0002-2154-4299
Oulu University Hospital · FIUniversity of Oulu · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Proper functioning of each secretory and endocytic compartment relies on its unique pH micro-environment that is known to be dictated by the rates of V-ATPase-mediated H

Indexed as

AnimalsCell Line, TumorCell MovementCell ProliferationChloride-Bicarbonate AntiportersChlorocebus aethiopsCOS CellsGlycosylationGolgi ApparatusHumansHydrogen-Ion ConcentrationRNA InterferenceRNA, Small InterferingUp-RegulationChloride-Bicarbonate AntiportersRNA, Small InterferingSLC4A2 protein, humanCancerGlycosylationGolgi apparatusInvasionNet acid efflux homeostasisProton leak

Identifiers

PMID34279699
PMCPMC8429400
OpenAlexW3185822494

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.