Observational studyInvestigative ophthalmology & visual science2021
Choroidal and Retinal Thickness and Axial Eye Elongation in Chinese Junior Students.
Observational study in Investigative ophthalmology & visual science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.
- Correlation between refractive errors and ocular biometric parameters in children and adolescents: a systematic review and meta-analysis.BMC ophthalmology · 2023Pooled it
- Effects of tropicamide and compound tropicamide eye drops on ocular biological parameters and choroid thickness in children.BMC ophthalmology · 2025Trial
- Anatomical and Transcriptional Alterations in the Mouse Choroid Induced by All-Trans Retinoic Acid.Investigative ophthalmology & visual science · 2026Article
- Aqueous Humour Cytokines as Predictors of Axial Elongation in High Myopia: A 2-Year Longitudinal Cohort Study.Clinical & experimental ophthalmology · 2026Observational
- Behavioral and Structural Correlates of Axial Length in School-Aged Children: Baseline Findings from the Seoul Myopia Cohort Study.Life (Basel, Switzerland) · 2026Article
- Peripheral Retinal Vessel Density in Children and Adolescents with Myopia: A Deep Learning Assessment.Ophthalmology and therapy · 2026Article
- Effects of small incision lenticule extraction and femtosecond laser-assistedExperimental and therapeutic medicine · 2026Article
- One-Month Changes in Choroidal Vascularity Index of Medium Vessel Layer in Children with Myopia Wearing Orthokeratology Lenses: a Predictor for One-Year Changes in Axial Length.Ophthalmology and therapy · 2025Article
- The Ocular Parameter Changes Caused by Reading With Remote Image Optical Screen.Translational vision science & technology · 2025Article
- Quantitative Choroidal Analysis of Molecularly Characterized Retinitis Pigmentosa.Investigative ophthalmology & visual science · 2025Article
- Fundus vascular arcades angle reflects choroidal thickness in highly myopic children and adolescents.Eye (London, England) · 2025Article
- Interocular differences in choroidal thickness and circulation in anisomyopic adults and their association with myopia severity.Frontiers in medicine · 2025Article
- Article
- Choroidal Vascularity and Axial Length Elongation in Highly Myopic Children: A 2-Year Longitudinal Investigation.Investigative ophthalmology & visual science · 2024Observational
- Choroidal thickness in patients with thyroid-associated ophthalmopathy, as determined by swept-source optical coherence tomography.The British journal of ophthalmology · 2024Article
- Peripapillary atrophy area predicts the decrease of macular choroidal thickness in young adults during myopia progression.BMJ open ophthalmology · 2024Article
- Sympathetic nervous system activity is associated with choroidal thickness and axial length in school-aged children.The British journal of ophthalmology · 2024Article
- Choroidal Morphology and Photoreceptor Activity Are Related and Affected by Myopia Development.Investigative ophthalmology & visual science · 2024Article
- Analysis of research hotspots and trends in pediatric ophthalmopathy based on 10 years of WoSCC literature.Frontiers in pediatrics · 2024Article
- Correlation between choroidal thickness and the degree of myopia.Technology and health care : official journal of the European Society for Engineering and Medicine · 2024Article
Corrections and comments
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Authors and funding
17 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: To explore the associations between macular choroidal and retinal thickness and axial elongation in non-myopic and myopic junior students. Methods: In this school-based longitudinal observational study, axial length was measured by optical low-coherence reflectometry, and choroidal thickness and retinal thickness were measured by spectral-domain optical coherence tomography. Myopia was defined as non-cycloplegic objective spherical equivalent refraction ≤ -0.50 diopters. Structural equation modeling and multiple linear regression models were used to analyze the associations between baseline choroidal and retinal thickness with axial elongation. Results: Out of 1307 students examined at baseline in 2017, 1197 (91.58%) returned for follow-up examination in 2018, with a median age of 12.00 years (interquartile range [IQR], 1.00) and included 667 boys (55.72%). Within a 1-year period, the median axial elongation of right eyes was 230 µm (IQR, 180) in boys and 200 µm (IQR, 160) in girls (P = 0.032). The thinner temporal choroidal thickness was associated with greater 1-year axial elongation only in myopic students (β, -0.20; 95% confidence interval [CI], -0.37, -0.03), the thinner temporal retinal thickness was associated with greater 1-year axial elongation in both non-myopic (β, -2.67; 95% CI, -4.52, -0.82) and myopic (β, -0.99; 95% CI, -1.68, -0.30) students, after adjustment for sex, age, and height. Subfoveal and nasal choroidal and retinal thickness were not significantly associated with axial elongation in either non-myopic or myopic students. Conclusions: A thinner temporal choroid at age 12 years may predict greater 1-year axial elongation in myopic students, and a thinner temporal retina may predict greater 1-year axial elongation in both non-myopic and myopic students. This finding may help to identify children at risk and control axial elongation with potential preventive strategies.
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Registered trials
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