Evidence map›Paper›PMID 34279488›Full record

ArticleJournal of visualized experiments : JoVE2021

Fluorescence Microscopy for ATP Internalization Mediated by Macropinocytosis in Human Tumor Cells and Tumor-xenografted Mice.

Corinne M Nielsen, Yanrong Qian, Subhodip Adhicary, Yunsheng Li, Pratik Shriwas, Xuan Wang, Lindsey Bachmann, Xiaozhuo Chen

Abstract readVideo-Audio Media
In one paragraph

Article in Journal of visualized experiments : JoVE, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Corinne M Nielsen *Department of Biological Sciences, Ohio University; Molecular and Cellular Biology Program, Ohio University; Neuroscience Program, Ohio University.
Yanrong Qian *Edison Biotechnology Institute, Ohio University.
Subhodip AdhicaryDepartment of Biological Sciences, Ohio University; Translational Biomedical Sciences Program, Ohio University.
Yunsheng LiEdison Biotechnology Institute, Ohio University.
Pratik ShriwasDepartment of Biological Sciences, Ohio University; Molecular and Cellular Biology Program, Ohio University; Edison Biotechnology Institute, Ohio University.
Xuan WangDepartment of Biological Sciences, Ohio University; Molecular and Cellular Biology Program, Ohio University; Edison Biotechnology Institute, Ohio University.
Lindsey BachmannHonors Tutorial College, Ohio University.
Xiaozhuo ChenDepartment of Biological Sciences, Ohio University; Molecular and Cellular Biology Program, Ohio University; Edison Biotechnology Institute, Ohio University; Department of Biomedical Sciences, Heritage College of Osteopathic Medicine, Ohio University; chenx@ohio.edu.

Funding

Extracellular ATP in cancer: mechanism study of ATP internalization and ATP-induced drug resistance in cancer cells and tumorsR15CA242177 · NCI · OHIO UNIVERSITY ATHENS · PI CHEN, XIAOZHUO · 2019 to 2019
$450k
NCI NIH HHS R15 CA242177
6 · The paper itself

Abstract

Adenosine triphosphate (ATP), including extracellular ATP (eATP), has been shown to play significant roles in various aspects of tumorigenesis, such as drug resistance, epithelial-mesenchymal transition (EMT), and metastasis. Intratumoral eATP is 10

Indexed as

Adenosine TriphosphatePinocytosisAnimalsCell Line, TumorEndocytosisHumansMiceMicroscopy, FluorescenceAdenosine Triphosphate

Identifiers

PMID34279488
PMCPMC9730898

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.