Evidence map›Paper›PMID 34279454›Full record

ReviewJournal of clinical medicine2021

Autoimmune Brainstem Encephalitis: An Illustrative Case and a Review of the Literature.

Romy Zoghaib, Ali Sreij, Nancy Maalouf, Joumana Freiha, Raghid Kikano, Naji Riachi, Moussa A Chalah, Samar S Ayache, Rechdi Ahdab

Open access · goldAbstract readReview
In one paragraph

Review in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.4field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 18 citations in OpenAlex.

  1. Suspected encephalitis in adults.Practical neurology · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Autoimmune Encephalitis and Related Syndromes.Journal of clinical medicine · 2023
    Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Romy ZoghaibGilbert and Rose Mary Chagoury School of Medicine, Lebanese American University, Byblos 4504, Lebanon.
Ali SreijGilbert and Rose Mary Chagoury School of Medicine, Lebanese American University, Byblos 4504, Lebanon.
Nancy MaaloufGilbert and Rose Mary Chagoury School of Medicine, Lebanese American University, Byblos 4504, Lebanon.
Joumana FreihaGilbert and Rose Mary Chagoury School of Medicine, Lebanese American University, Byblos 4504, Lebanon.
Raghid KikanoGilbert and Rose Mary Chagoury School of Medicine, Lebanese American University, Byblos 4504, Lebanon.ORCID 0000-0002-7772-8783
Naji RiachiGilbert and Rose Mary Chagoury School of Medicine, Lebanese American University, Byblos 4504, Lebanon.
Moussa A ChalahService de Physiologie-Explorations Fonctionnelles, Hôpital Henri Mondor, Assistance Publique-Hôpitaux de Paris, 51 Avenue de Lattre de Tassigny, 94010 Créteil, France.ORCID 0000-0002-0880-8608
Samar S AyacheService de Physiologie-Explorations Fonctionnelles, Hôpital Henri Mondor, Assistance Publique-Hôpitaux de Paris, 51 Avenue de Lattre de Tassigny, 94010 Créteil, France.ORCID 0000-0003-0188-1957
Rechdi AhdabGilbert and Rose Mary Chagoury School of Medicine, Lebanese American University, Byblos 4504, Lebanon.
University Medical Center Rizk Hospital · LBUniversité Paris-Est Créteil · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autoimmune brainstem encephalitis (BSE) is a rare neurological condition with a wide range of underlying etiologies. It can be subdivided into two broad groups: a primary inflammatory disease of the central nervous system (CNS) or a brainstem disorder secondary to systemic diseases where the CNS is only one of many affected organs. Symptoms range from mild to life-threatening manifestations. Most cases respond well to immunotherapy. Therefore, broad and in-depth knowledge of the various inflammatory disorders that target the brainstem is essential for guiding the diagnostic approach and assisting in early initiation of appropriate therapy. We herein report on a case of BSE and provide an overview of the various causes of autoimmune BSE with an emphasis on the clinical manifestations and diagnostic approach.

Indexed as

acute disseminated encephalomyelitisautoimmune glial fibrillary acidic protein astrocytopathyBickerstaff brainstem encephalitisbrainstem encephalitisCLIPPERSconnective tissue diseasemultiple sclerosisneuromyelitis optica spectrum disorderparaneoplastic syndromes

Identifiers

PMID34279454
PMCPMC8269049
OpenAlexW3174631563

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.